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Wuhan Yuancheng Gongchuang Technology Co,ltd
China Mannitol High Quality Diuretic Medication CAS 87-78-5 Mannitol manufacturer |
2nd
Gold Index: 161482
Qty (Other,g) | Unit Price (59.0~89.0 USD) |
100 - 199 | 59 |
200 + | 89 |
Payment Terms: | T/T,WU,Money Gram;bitcoin |
Place of Origin: | Hubei, China (Mainland) |
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Mannitol
Usage of High quality GMP pharma grade/Pharmaceutical grade Mannitol
1.Mannitol powder can be good diuretic , reducing intracranial pressure , intraocular pressure .
2.Mannitol powder can be tablets excipient and solid , liquid diluent .
3.Mannitol powder can be the minimum water imbibition in sugar and sugar alcohol, and has refreshing sweetness.
4.Mannitol powder can be tablet excipient and chewable taste masking agent .
Mannitol Synonyms: DL-Mannitol; Hexahydroxyhexane
Mannitol CAS: 69-65-8
Mannitol EINECS: 200-711-8
Mannitol Assay: 99% min.
Mannitol Standard: BP/EP/USP
Mannitol Packing: 25kg/cardboard drum
Mannitol Character: Colorless to white needle-like or rhombic columnar crystals or crystalline powder. Odorless, has a cool sweet taste. Sweetness of sucrose about 57% to 72%. 8.37J per g of heat generated is about half glucose.
Containing a small amount of sorbitol. The relative density of 1.49. Specific rotation [α] D20-0.40 ° (10% aqueous solution). Minimal moisture absorption. Solution stability. Of acid, dilute alkali stable. Oxidation by oxygen in air does not. Soluble in water (5.6g/100ml, 20 ºC) and glycerol (5.5g/100m1). Slightly soluble in ethanol (1.2g/100m1). Soluble in hot ethanol. Almost insoluble in most other common organic solvents. 20% aqueous solution of pH 5.5 to 6.5.
Usage: Mannitol in medicine is a good diuretic to reduce intracranial pressure, intraocular pressure and renal pharmaceuticals, dehydration, sugar substitutes, also used as tablet excipients and solid, liquid diluent. Mannitol injection as a high penetration of antihypertensive pharmaceuticals, the clinical brain disorders, especially rescue the rescue of a pharmaceutical commonly used, to reduce intracranial pressure with antihypertensive pharmaceuticals require rapid, effective and accurate.
Used as a tablet excipient, mannitol no moisture absorption, fast drying, good chemical stability, but also has tasty, and good granulation Characters for anti-cancer pharmaceuticals, antibiotics, antihistamines, and vitamins and other large part of the tablet. In addition, pharmaceuticals used to sober up, mouth refreshing agent Chewable agent
Food additive, low-calorie sweetener; gum and candy anti-stick; nutritional supplement agents and tissue conditioner; moisturizer; filler.
the goods in the sugar and sugar alcohols in the minimum water absorption, and sweet with a refreshing, for maltose, chewing gum, cakes and other foods of anti-sticking, and as a general anti-sticking pastry flour. Diabetes can also be used with food, fitness and food low calorific value, low-sugar sweetener.
In industry, mannitol can be used for the plastics industry, the system glycerol rosin esters and synthetic resins, explosives, detonators (nitrification mannitol) and so on. In the chemical analysis for the determination of boron in biological testing for bacterial culture on the agent. Although mannitol can be absorbed by the gastrointestinal, but does not accumulate in the body. Is absorbed, is metabolized in the body part, other part in the urine; by can be obtained dibromo mannitol.
Reagents for the analysis, but also for synthetic resins and medicine
Application: Used for produce mannitol injection.
Product Description:
Name of the product | Mannitol |
Appearance | White or almost white, crystalline powder or free-flowing granules. |
Solubility | Freely soluble in water, very slightly soluble in ethanol (96 per cent). |
Identification | First identification C. Second identification A, B, D. A. Specific optical rotation (2.2.7): + 23 to + 25 (anhydrous substance). B. Melting point (2.2.14): 165 °C to 170 °C. C. Infrared absorption spectrophotometry (2.2.24). D. Thin-layer chromatography (2.2.27). |
Appearance of solution | The solution is clear (2.2.1) and colourless (2.2.2, Method II). |
Conductivity | Maximum 20 µS·cm-1. |
Reducing sugars | Maximum 0.2 per cent (calculated as glucose equivalent). |
Related substances | -impurities A, B: for each impurity, not more than the area of the principal peak in the chromatogram obtained with reference solution (b) (2.0 per cent); - impurity C: for the sum of the areas of the 2 peaks, not more than the area of the principal peak in the chromatogram obtained with reference solution (b) (2.0 per cent); - unspecified impurities: for each impurity, not more than twice the area of the principal peak in the chromatogram obtained with reference solution (c) (0.10 per cent); - total: not more than the area of the principal peak in the chromatogram obtained with reference solution (b) (2.0 per cent). |
Lead | Maximum 0.5 ppm. |
Nickel | Maximum 1 ppm. |
Water | Maximum 0.5 per cent, determined on 1.00 g. |
Microbial contamination | TAMC: acceptance criterion 102 CFU/g (2.6.12). |
Bacterial endotoxins | less than 2.5 IU/g |
ASSAY | 98.0 per cent to 102.0 per cent (anhydrous substance). |
3. Applications:
A. In the food industry, mannitol stearic acid fat for peanut pulp, can Prevent oil separation, used for cookies can make cookies crunchy, is Not easy to damp, used for candy can rise to finalize the design Function, improve the quality of candy.
B. As dehydration labels&tags diuresis medicine, mannitol can Reduce intracranial pressure and pressure inside the eye, eliminate Brain edema, diuresis and prevent early acute renal insufficiency, Preparations for mannitol injection.
C. In daily chemical industry, mannitol in XueHuaGao as emulsifier, Can make the XueHuaGao is exquisite.
D. In engineering, insulation, sound insulation is the important Material.
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Tools for homebrew: Filter,Crimper,Vials, caps, ect.
COA:
Item | specification |
Appearance | White crystalline powder |
Specific Rotation | +23°- +25° |
Melting Range | 165.0~170.0 |
Appearance of solution | Clear and colourless |
Conforms | ≤ 20μS/cm |
Reducing Sugars | ≤ 0.20% |
acidity | ≤ 0.30ml |
sulphate | ≤ 0.01% |
chloride | ≤ 0.005% |
Sulphate ash | ≤ 0.1 % |
oxalic acid | ≤ 0.02% |
Lead | ≤ 0.5ppm |
Nickel | ≤ 1ppm |
Water | ≤ 050% |
arsenic | ≤ 0.0002% |
Assay(dried) | 98.0%-102.0% |
Sorbitol | ≤ 2% |
Endotoxin | ≤ 2.5EU/g |
IP | Conforms |