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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Pregnenolone Steroid Hormone Estrogen Hormone Promestriene manufacturer

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Pregnenolone Steroid Hormone Estrogen Hormone Promestriene 

Price: 90.0 USD 
Payment Terms: T/T,D/A,WU,Money Gram;Bitcoin 
Special Groups: Bodybuilding Suppplements (165)
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: Polypeptides
Production Capacity: 500kg//month
Delivery Date: 4-15days
CAS No.: 863288-34-0
Alias: Promestriene powder
Usage: Promestriene price
Price: Promestriene for sale
Effects: Pregnenolone for sale
Standard: Pregnenolone bulk sale
Means of Transport: Ocean,Air;Express
Packing: disguise package or as requ...
Brand Name: yc
Purity: Pregnenolone effect
Package: Promestriene supplier
Supplier: buy Promestriene
Delivery: Pregnenolone powder
Appearance: Pregnenolone usage

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Topical Estrogen Supplements Pharmaceutical Raw Materials CAS 39219-28-8 Promestriene

Product Name : Promestriene
Synonyms : PROMESTRIENE;17-BETA-ESTRADIOL 3-PROPYL ETHER 17-METHYL ETHER;1,3,5(10)-ESTRATRIEN-3,17-BETA-DIOL 3-PROPYL ETHER 17-METHYL ETHER;3-propoxy-17beta-methoxy-1,3,5(10)-estratriene;3-Propoxy-17-methoxyoestra-1,3,5(10)-triene;
3-Propoxy-17b-methoxyestra-1,3,5(10)-trien;17(b)-17-Methoxy-3-propoxy-estra-1,3,5(10)-triene;17()-17-Methoxy-3-propoxy-estra-1,3,5(10)-triene
Promestriene CAS : 39219-28-8
Promestriene MF : C22H32O2
Promestriene MW : 328.49
Promestriene EINECS : 254-361-6
Promestriene Product Categories : APIs;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids
Promestriene Melting point : 64-660C
Storage temp. : -20°C Freezer
Chemical Properties : White Solid
Usage    : Estradiol derivative .
Usage    : A synthetic diethyl-ether of Estradiol with no distal hormonal effects, in patients undergoing surgical correction for stress urinary incontinence (SUI) .


Promestriene Outline    
Promestriene is a topical estrogen supplements studied and developed by Monaco Dudley beauty pharmaceutical companies (wholly purchased by Merck Company of the United State in 1999) and has gotten the US patent approval in 1977 with the formulation reagents mainly including the Colpotrophine which entered into market in 1975 in France and Delipoderm which entered into the French market in 1978, promestriene, colpotrophine (promestriene soft capsules and cream) and chlorquinaldol. Promestriene (chloroquinaldol/ Promestriene vaginal tablets) have been collected by Martindale Drug Manual and have entered into market in more than 40 foreign countries for over 40 years. Currently, in many countries, Promestriene is still the first-line drugs for the treatment of vaginal infections and atrophic vaginitis. Clinical practice has shown that it is safe and effective with the patient being well tolerated . 

Promestriene is a kind of special estradiol diether with its special molecular structure making it cause the biological effects in situ without the necessity of exerting the effect after being metabolized. It has a biological half-life of being smaller than 24 h. Therefore, upon vaginal administration, drug will directly take effect on the vaginal mucosa without being absorbed by the mucosa. There is no accumulation of estrogen in the body, particularly in the estrogen-sensitive organs far away from the vagina. Clinical observation further noted that the topical administration of promestriene has no effect on the plasma sex hormone binding globulin (SHBG), estrone (E1), estradiol (E2), estriol (E3), LH and FSH, and can effectively prevent and treat the atrophic vaginitis with strict local estrogen effect. Compared with other drugs, advantages of promestriene lie in that it is hardly absorbed through the vagina, and thus being able to avoid the systemic risk of long-term vaginal topical supplement of estrogen with fewer adverse reactions which are of lesser extent and no systemic effects. It only has mild side effect and high safety, and the vast majority of patients are willing to accept, and therefore is an excellent choice for the treatment of atrophic vaginitis, especially for those with estrogen-dependent diseases .


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Top Quality Estrogen Steroid Powder CAS : 145-13-1 Pregnenolone
Pregnenolone Product name: Pregnenolone 
Pregnenolone English Synonyms: DELTA5-PREGNEN-3BETA-OL-20-ONE;DELTA5-PREGNEN-3B-OL-20-ONE;DELTA-5-PREGNENE-3B-OL-20-ONE;DELTA5-PREGNENOLONE;1-((3S,8S,9S,10R,13S,14S,17S)-3-HYDROXY-10,13-DIMETHYL-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-17-YL)-ETHANONE;3BETA-HYDROXY-5-PREGNEN-20-ONE;3BETA-HYDROXYPREGN-5-EN-20-ONE;3b-hydroxy-5-pregnen-20-one
Pregnenolone  CAS NO.: 145-13-1
Pregnenolone  Assay: 99%
Pregnenolone  Molecular Formula:C21H32O2
Pregnenolone  Molecular Weight:316.48
Pregnenolone  Quality Standard: Enterprise Standard
Pregnenolone  Packing:1kg/foil bag
Pregnenolone  Appearance: White or almost white crystalline powder
Pregnenolone  Usage: White crystalline powder. Melting point 193 ºC. Insoluble in water.
Pregnenolone  Use for biochemical studies. Progesterone hormone class medicine intermediate

 Specification



Test item

Specifications

Character

White or almost white crystalline powder

Specific rotation

+75 º to +80 º

Identification

Complies by IR
Complies by TLC

Chromatographic purity

Only one principal impurity more than 1.0% and not more than 2.0. other impurity not more than 1.0%

Loss on drying

Not more than 0.5%


≤60ppm

Assay

97.0% to 102.0%




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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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