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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Topical Pain Relief Local Anesthetic Raw White Powder Levobupivacaine Hydrochloride manufacturer

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Gold Index: 167643

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Topical Pain Relief Local Anesthetic Raw White Powder Levobupivacaine Hydrochloride 

Price: 1.0 USD 
Payment Terms: T/T,WU,Money Gram;BItcoin 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: pain killer
Production Capacity: 5000kg per month
Delivery Date: within 24 hours after payme...
CAS No.: 27262-48-2
color: white
Alias: Levobupivacaine hydrochlori...
MOQ: 1 kg
payment methods: T/T, Westeron Union, Money ...
Delivery time: 5-7 days
Means of Transport: Ocean,Air;express
Packing: disguised package
Brand Name: Levobupivacaine Hydrochlori...
Purity: 99%
appearence: powder
Standard: USP 32
package: safe discreet package
lead time: within 24hour after payment...
Shipping Methods: ship by DHL,UPS,HKEMS,Fedex...

Levobupivacaine hcl is a sodium channel blocker
Levobupivacaine hcl is a long-acting local anaesthetic for epidural anesthesia
Levobupivacaine hcl

Effective Anti - Pain Local Anesthetic Drug Levobupivacaine Hydrochloride


1. Levobupivacaine Hydrochloride Basic Information


Name: Levobupivacaine hydrochloride

CAS No.: 27262-48-2

Formula: C18H29ClN2O

Molecular Weight: 324.89

Melting Point: 254 °C (dec.)(lit.)

Boiling Point: 423.4 °C at 760 mmHg

Flash Point: 209.9 °C

Appearance: white crystalline powder

Usage: relieve pain


2. Levobupivacaine Hydrochloride Specifications:



Test Items
SpecificationTest Results
DescriptionWhite or almost white crystalline powderWhite crystalline powder
Melting Point191.0~193.0ºC192ºC
Loss of drying≤1.0%0.5%
Heavy Metal≤20ppm15ppm
TLCOnly one spotOnly one spot
Assay≥99.5%99.91%
ConclusionIt complies with the USP 32.



3.Levobupivacaine Hydrochloride Description:


Levobupivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine.It is the hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property.


Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and transmission of nerve impulses  (stabilizing neuronal membrane),  thereby resulting in analgesia and anesthesia. In comparison with racemic bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action.


Levobupivacaine hydrochloride is a sodium channel blocker used as a long-acting local anaesthetic for epidural anesthesia. Levobupivacaine is the isomer of bupivacaine, with efficacy similar to that of bupivacaine with a reduced risk of cardiotoxicity.


4.Levobupivacaine Hydrochloride Application:


Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by Abbott under the trade name Chirocaine. Bupivacaine is an amide-type local anaesthetic. Although it blocks neuro transmission, its membrane stabilising action also affects the myocardium. This can cause fatal cardiotoxicity. As bupivacaine is widely used in surgery and obstetrics, attempts have been made to develop a safer long-acting local anaesthetic.

 

The bupivacaine molecule is a racemic compound. Levobupivacaine is the S-enantiomer of bupivacaine and is thought to have less cardiotoxic potential than the R-enantiomer. The pharmacokinetic parameters of levobupivacaine are similar to those of bupivacaine.


Levobupivacaine has been studied in surgical anaesthesia and for pain management. It can be used for local infiltration, epidural, intrathecal and peripheral nerve blocks. For epidural analgesia it can be given with  clonidine. Double-blind comparisons of levobupivacaine and bupivacaine show that their anaesthetic effects are similar.


5.Levobupivacaine Hydrochloride Clinical Common usage


Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by Abbott under the trade name Chirocaine.


Compared to bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action. It is approximately 13 percent less potent (by molarity) than racemic bupivacaine and has a longer motor block onset time. Levobupivacaine is indicated for local anaesthesia including infiltration, nerve block, ophthalmic, epidural and intrathecal anaesthesia in adults; and infiltration analgesia in children.


6.Other topical pain relief powders 
 

BenzocaineCAS:94-09-7 
Benzocaine hydrochlorideCAS:23239-88-5 
Tetracaine hydrochlorideCAS:136-47-0
ProcaineCAS:59-46-1 
TetracaineCAS:94-24-6 
Pramoxine HydrochlorideCAS:637-58-1
Procaine HClCAS:51-05-8
LidocaineCAS:137-58-6
Dibucaine hydrochlorideCAS:61-12-1
PrilocaineCAS:721-50-6
Propitocaine hydrochlorideCAS:1786-81-8
Proparacaine hydrochlorideCAS:5875-06-9
Lidocaine hydrochlorideCAS:73-78-9
Articaine hydrochlorideCAS:23964-57-0
Levobupivacaine hydrochlorideCAS:27262-48-2
Ropivacaine hydrochlorideCAS:132112-35-7
BupivacaineCAS:2180-92-9
Bupivacaine hydrochlorideCAS:14252-80-3


7.Order Process and Tips 


Make an orderPlease make clear what product and what quantity you need
Mini Order100g, negotiable
QuotePrices and Specification details(COA) would be offered for you to consider and confirm
Payment waysT/T, Bank Transfer, Western Union, Paypal, Money Gram and Bitcoin
Delivery waysAll Express Modes(EMS, DHL, TNT, FedEx, UPS, etc.)
Shipping addressProvide your Valid and Correct destination address info(if possible with post code, phone number).
PackingSelect best ways according to quantity and safety degree(Super discreet, professional and experienced)
Lead timeWithin 12 hours upon receipt of payment
Package picturesPhotos of parcel would be offered to tell apart the items
Tracking numberOffered once it is released
Shipping time3-7 working days (Door-to-Door)
After-sale service24/7 Online for any problems


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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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