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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Pharmaceutical Raw Materials Poloxamer 407 manufacturer

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Pharmaceutical Raw Materials Poloxamer 407 

Price: 1.0 USD 
Payment Terms: T/T,WU,Money Gram;BItcoin 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: pharm raw material
Production Capacity: 5000kg per month
Delivery Date: within 24 hours after payme...
CAS No.: 9003-11-6
color: white
grade: Pharmaceutical grade
Usage: Pharmaceutical material, St...
Alias: Poloxamer 407
delivery time: 5-7 days
Means of Transport: Ocean,Land,Air;express
Packing: disguised package
Brand Name: Poloxamer 407
Purity: 99%
appearence: crystalline powder
Melting Point: 60-50ºC
Standard: USP30
lead time: within 24hours after paymen...
shipping methods: ship by HKEMS, DHL,UPS, FED...

Poloxamer 407 strengthen stamina, vigour and physical strength;
Poloxamer 407 improve the reactive sensitivity
Poloxamer 407 improve stress strength

Pharmaceutical Grade White Crystal Powder Poloxamer 407 


Poloxamer 407

Synonyms:BLOCK COPOLYMER OF POLYETHYLENE AND POLYPROPYLENE GLYCOL; SYNPERONIC F 108; SYNPERONIC L 121; SYNPERONIC L 122; SYNPERONIC P 105; SYNPERONIC P 85; SYNPERONIC PE(R)/F68; SYNPERONIC PE(R)/L61

CAS Registry Number:9003-11-6

Molecular Formula:HO(C2H4O)a(C3H6O)b(C2H4O)aH

Molecular Weight:102.13

Appearance:White crystalline powder

Density:1.095 g/mL at 25 °C

Boiling Point:32.9 °C at 760 mmHg

Melting Point:60-50ºC

Flash Point:55.2 °C

Refractive index:n20/D 1.466

Solubility:H2O: at <70 °Csoluble

 

Description :


Poloxamer is a synthetic block copolymer of ethylene oxide and propylene oxide. It is available in several types, conforming to the following requirements.


Poloxamer were firstly developed by America.They have almost no toxicity, little irritation on the skin and the mucosa. They are widely used as emulsifier, solubilizing agent, hydrophilic substrate of ointments and suppositories,artificial blood, artificial tear and artifical skin etc.


Usage:


Poloxamer 407 can strengthen stamina, vigour and physical strength;

Poloxamer 407 can improve the reactive sensitivity;

Poloxamer 407 can improve the stress strength;

Poloxamer 407 can promote function of sex hormone, ease the pain of muscle;

Poloxamer 407 can improve the function of cardiac muscle,;

Poloxamer 407 can improve the organism metabolism.


Application:


1.Because of their amphiphilic structure, the polymers have surfactant properties that make them useful in industrial applications. Among other things, they can be used to increase the water solubility of hydrophobic, oily substances or otherwise increase the miscibility of two substances with different hydrophobicities. For this reason, these polymers are commonly used in industrial applications, cosmetics, and pharmaceuticals. They have also been evaluated for various drug delivery applications and were shown to sensitize drug resistant cancers to chemotherapy.


2.In bioprocess applications, poloxamers are used in cell culture media for their cell cushioning effects because their addition leads to less stressful shear conditions for cells in reactors.


3.In materials science, the poloxamer P123 has recently been used in the synthesis of mesoporous materials, including SBA-15.


Specification


Standard adoptedUSP-NF, EP and JPE requirements
Items of analysisSpecificationResults
 Identification (IR)Standard Scan
 
Matches
 
Appearance of SolutionLess than BY7Pass
Clarity and color of solutionClear and colorlessPass
AcidRed SolutionPass
pH value (25g/L in water)5.0-7.56.8
pH value (100g/L in water)5.0-7.57.0
Average Molecular Weight9840-14600g/mol13036 g/mol
Oxyethylene71.5-74.9%72.5 %
Total Ash<=0.4%0.2%
Residue On Ignition<=0.30%0.3%
Unsaturation0.031-0.065mEq/g0.056mEq/g
Water<=0.75%0.05%
Heavy MetalsLess than 0.002%Pass
BHT Stabilizer50-125ppm104ppm
Congealing Point50-62°C52°C
APHA Color (50:50 in MeOH)<=12060
Cloud Point, 10% solution>=100°C> 100°C
Residual Solvent USP RequirementsMeets
Sum Ethylene and Diethylene Glycol<=5.0ppm0.1ppm
Ethylene Oxide<=1.0ppm0.1ppm
 Propylene Oxide 
<=5.0ppm
0.8ppm
ArsenicLess than 2 ppmPass
ConclusionQualified


Our advantages: 


A. Our company is a professional raw powder factory in China for over 10 years, all powders are factory directly supplying. 

B. Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and many other countries, over 100kgs each month. 

C. Professional team special for package and shipment and staring on tracking code 24hours for customs pass guaranteed. 100% pass to UK, Norway, Poland, Spain, USA, Canada, Brazil; 98% pass to Germany, Russia, Australia, New Zealand. 

D. Most of powders are in stock, Chargeable samples are available, Could be shipped out within 24hours. 

E. High quality, good price, fast and safety delivery. Shipment by DHL , FedEx, HKEMS, UPS, etc. 


Ms. Selina Hu
skype Ms. Selina Hu
Sales Manager
Tel: 86-27-88211875
Mobile: 188 7222 0826
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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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