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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Pharmaceutical Grade Raw Material CAS 55079-83-9 Etretin Acitretin manufacturer

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Pharmaceutical Grade Raw Material CAS 55079-83-9 Etretin Acitretin 

Price: 1.0 USD 
Payment Terms: T/T,WU,Money Gram;BItcoin 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: pharm raws
Production Capacity: 5000kg per month
Delivery Date: within 24 hours after payme...
CAS No.: 55079-83-9
Acitretin color: yellow
Acitretin Alias: Etretin, Acitretin
Acitretin MOQ: 1 kg
Acitretin payment methods: T/T, Westeron Union, Money ...
Acitretin Delivery time: 5-7 days
Means of Transport: Ocean,Air;express
Packing: disguised package
Brand Name: Acitretin
Purity: 99%
Acitretin appearence: powder
Acitretin Standard: EP6.0
Acitretin package: safe discreet package
Acitretin lead time: within 24hour after payment...
Acitretin shiipping methods: ship by DHL,UPS,HKEMS,Fedex...

Acitretin is taken orally.
Acitretin is typically used for psoriasis.
Acitretin is a second generation retinoid.
Acitretin raw powder bulk price

Acitretin Pharmaceutical Raw Yellow Powder Acitretin


Acitretin detail


Product: Acitretin

Category: A synthetic retinoid

CAS:55079-83-9

MF: C21H26O3

MW:326.43

EINECS:259-474-4

Character: Yellow or light orange crystalline powder

MP: 228-230°C

Assay: 99%min

storage temp: 2-8°C

Package: 100G/500G/1KG/bag

Description: A synthetic retinoid which is the major metabolite of etretinate.


Acitretin Descrption


1. Acitretin is a second generation retinoid. It is taken orally, and is typically used for psoriasis. It is a metabolite of etretinate, which was used prior to the introduction of acitretin.


Etretinate was discontinued because it had a narrow therapeutic index as well as a long elimination half-life (t1/2=120 days), making dosing difficult. In contrast, acitretin's half-life is approximately 2 days. Because acitretin can be reverse metabolised into etretinate which has a long half life, women must avoid becoming pregnant for at least 2 years after discontinuing acitretin. Therefore, etretinate is generally not recommended for women of child bearing age with a risk of becoming pregnant.


2. Acitretin is the least toxic systemic treatment for psoriasis. It is an oral retinoid of choice used in the treatment of severe resistant psoriasis. It binds to nuclear receptors that regulate gene transcription. They induce keratinocyte differentiation and reduce epidermal hyperplasia. Acitretin is readily absorbed and widely distributed after oral administration. A therapeutic effect occurs after 2 to 4 weeks or longer. If a patient has received the medication, he/she is advised against giving blood for at least 3 years due to the risk of birth defects.


Acitretin Application


For the treatment of psoriasis (severe refractory cases, including erythrodermic andgeneralized pustular), severe refractory oral lichen planus, keratosis refractory severeintractable disorders (such as ichthyosis-like skin disease, congenital ichthyosis-likeerythroderma, lamellar ichthyosis and other ichthyosis), follicular keratosis, palmoplantarkeratosis, pityriasis rubra pilaris, palmoplantar pus fibromatosis.


Acitretinis widely applied in pharmaceutical field, mainly used for the cure of dermatonosus like acne, ichthyosis and psoriasis abnormal, etc..


For skin keratinocytes-resistant drugs and cell-induced differentation drug.


Acitretin Specification


ItemSpecificationsResults
DescriptionA yellow or greenish-yellow,
crystalline powder
Conforms
IdentificationShall complyAll comply
Loss on drying≤0.5%0.1%
Sulphated Ash≤0.1%0.04%
Heavy metals≤0.002%<0.002%
Palladium≤0.001%Not examined
Particle size
Tapped density
Loose density
100%<60umConforms
0.386g/ml
0.205g/ml

Related Substances
Individual Impuriti

Total Impurities


≤0.3%
≤1.0%


0.23%
0.36%

Assay (on dried basis)98%to102.0%99.8%
ConclusionThe results conforms with EP6.0 standards


How to Proceed Your Orders?


Step 1
Please let me know the items you are favorable, quantities, and the destination country.


Step 2
You confirm all details, and offer us purchasing order.


Step 3
We send the detail price of our product and offer the suitable shipping method for reference.


Step 4
You confirm the order and pay money 100% in advance and send us the detailed contacting information, including contacting person/company, address, mobile number, ZIP code and your special requirements.


Step 5
Parcel would be arranged within 12 hours upon receipt of your payment .
Photos would be offered to tell apart the products .
Tracking number :
Send by EMS, the tracking number is availabe within 12 hours . The info would be trackable that day or 1 day later.
If send by HKEMS or other express,the tracking number would be provided next day. And this does not mean the info is trackable that day. It would be released on internet 2 or 3 days later . The reason why is that parcel should be shipped to Hongkong from forwarder then wait for the flight.
You sign for the parcel , deliveried.


Step 6
We offer after-sales service after you receive parcel.


Ms. Selina Hu
skype Ms. Selina Hu
Sales Manager
Tel: 86-27-88211875
Mobile: 188 7222 0826
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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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