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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Plant Extract Veterinary Grade Sanguinarine Chloride manufacturer

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Gold Index: 167636

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Plant Extract Veterinary Grade Sanguinarine Chloride 

Price: 90.0 USD 
Payment Terms: T/T,D/A,WU,Money Gram;Bitcoin 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: Sanguinarine powder
Production Capacity: 500kg//month
Delivery Date: 4-15days
CAS No.: 5578-73-4
Alias: Sanguinarine
usage: Sanguinarine
price: Sanguinarine price
effects: Sanguinarine
Appearance: Sanguinarine powder
Means of Transport: Ocean,Air;Express
Packing: disguise package or as requ...
Brand Name: gongchuang
Purity: 99%
source: Sanguinarine from China
supplier: Sanguinarine supplier
Usage: Sanguinarine for medical
purity: 99% Sanguinarine
Standard: USP/BP/USP Sanguinarine

1,Sanguinarine is a toxic quaternary ammonium salt;
2.Sanguinarine is a potent inhibitor of NF-kappaB activation;
3,Sanguinarine powder for sale

Macleaya Cordata Extract

 

Botanical Source: Macleaya cordata (Willd.) R. Br.

Plant Part Used: Whole herb

Active Ingredients: Sanguinarine, Chelerythrine, protopine, α-Allocryptopine, β-Allocrytopine 

Specification: Total alkaloids 60%, 98%; Sanguinarine 45%; Chelerythrine 15%;

Sanguinarine Molecular formula: C20H14NO4

Sanguinarine Molecular weight: 332.335

Specifications: 50%, 98% HPLC

Sanguinarine Functions: 

1) Sanguinarine has been show to be reversible inhibitors of the enzymatic hydrolysis of acetylthiocholine. 

2) Sanguinarine ( pseudochelerythrine) is a potent inhibitor of NF-kappaB activation, IkappaBalpha phosphorylation, and degradation. 

3) Sanguinarine was reported that a study was made of a possible inhibitory action on the enzymatic hydrolysis of acetylthiocholine by human erythrocyte acetylcholinesterase of principal alkaloids isolated from Chelidonium majus L. And Macleaya cordata and microcarpa, and of drugs Ukrain and Sanguirythrine. Among all examined agents berberine, sanguinarine and Sanguirythrine were the strongest inhibitors of this reaction. Judging from the data obtained, sanguinarine and chelerythrine exert similar inhibitory effects on the reaction of enzymatic hydrolysis of acetylthiocholine.


Sanguinarine Description: 

Macleaya cordata extract is a green pollution-free plant extract. Macleaya cordata contains several alkaloids including sanguinarine, chelerythrine, protopine, and allocryptopine. Sanguinarine and chelerythrine are the main components of it, which have fungicidal and insecticidal activity. Sanguinarine is a potent inhibitor of NF-kappaB activation, IkappaBalpha phosphorylation, and degradation. It was been 

shown to be reversible inhibitors of the enzymatic hydrolysis of acetylthiocholine.

 Specification Sheet



Item

Index

Appearance

Lightorange powder

Content

Sanguinarine>1.5%
≥ 20% (sanguinarine>15%, chelerythrine>5%)
≥ 60% (sanguinarine>45%, chelerythrine>15%)
≥ 80% (sanguinarine>60%, chelerythrine>20%)

Water Insoluble

≤1.0%

Particle size

100% pass 80 mesh sieve
 



Introduction of Sanguinarine

Sanguinarine is a toxic quaternary ammonium salt from the group of benzylisoquinoline alkaloids. It is extracted from some plants, including bloodroot (Sanguinaria canadensis), Mexican prickly poppy Argemone mexicana, Chelidonium majus and Macleaya cordata. It is also found in the root, stem and leaves of the opium poppy but not in the capsule.

Sanguinarine is a toxin that kills animal cells through its action on the Na+-K+-ATPase transmembrane protein. Epidemic dropsy is a disease that results from ingesting sanguinarine.

If applied to the skin, sanguinarine kills cells and may destroy tissue. In turn, the bleeding wound may produce a massive scab, called an eschar. For this reason, sanguinarine is termed anescharotic.

Preliminary pre-clinical in vitro and in vivo studies have demonstrated that sanguinarine causes apoptosis in human cancer cells, and recommend study of sanguinarine as a potential cancer treatment.A study conducted by the Case Western Reserve University in 2000 found that low doses of sanguinarine caused this apoptosis in cancerous human epidermoid carcinoma cells while little reaction from normal human skin cells was observed. However, no products containing sanguinarine are currently approved by the FDA for the treatment of cancer; the FDA warns that unapproved bloodroot preparations are ineffective and dangerous.


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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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