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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Anti-pregnancy Mifepristone / RU-486 For Abortifacient powder CAS 84371-65-3 manufacturer

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Anti-pregnancy Mifepristone / RU-486 For Abortifacient powder CAS 84371-65-3 

Price: 1.0 USD 
Payment Terms: T/T,WU,Money Gram 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: steroid estrogen powder
Production Capacity: 500kgs/month
Delivery Date: within 48hours after receiv...
CAS No.: 84371-65-3
Apperance: white powder
Qualitification: ISO 9001, KOSHER,UKAS
Grade: Medical grade
Means of Transport: Ocean,Land,Air;Courier Expr...
Packing: safety and discreet pkg
Brand Name: YCGC
Purity: 98%
Payment: T/T,West Union,Money Gram,e...
Usage: Progesterone is used as a m...
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Mifepristone, also known as RU-486, is a medication typically used with misoprostol to bring about an abortion.This combination is more than 95% effec

Anti-pregnancy Mifepristone / RU-486 For Abortifacient powder  CAS 84371-65-3


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Mifepristone description:

Mifepristone, also known as RU-486, is a medication typically used with misoprostol to bring about an abortion.This combination is more than 95% effective during the first 50 days of pregnancy. It is also effective in the second trimester of pregnancy.Two weeks after use effectiveness should be verified. It is taken by mouth.


Common side effects include abdominal pain, feeling tired, and vaginal bleeding. Serious side effects may include heavy vaginal bleeding, bacterial infection, and a malformed baby if the pregnancy does not end. If used, appropriate follow up care needs to be available. Mifepristone works by blocking the effects of progesterone and causing contractions of the uterus.


Mifepristone Basic information

Product Name:Mifepristone

Synonyms: 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(1-propynyl)-estra-9-dien-3-one;11beta-[4-(n,n-dimethylamino)phenyl]-17alpha-(prop-1-ynyl)-delta4,9-estradiene;17-beta)-(11-bet;17beta)-11-[4-(dimethylamino)-phenyl]-17-hydroxy-17-(1-propynyl)estra-(11bet;17-beta-hydroxy-11-beta-(4-dimethylaminophenyl-1)-17-alpha-(prop-1-ynyl)oest;-17beta-ol-3-one;4,9-dien-3-one;r38486

CAS: 84371-65-3

MF: C29H35NO2

MW: 429.59

Product Categories: Steroids;Hormone;Acetylenes;Biochemistry;Functionalized Acetylenes;Hydroxyketosteroids;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Intracellular receptor;Nuclear Receptors;Steroid and Hormone;API;Hormone D rugs

Instructions

Oral administration has anti-pregnancy effect, currently applied for people with pregnancy<49 days. Specific usage in three: 

The first usage: orally administration of 600 mg mifepristone in single dose, place 1mg PGF2α (Kaposi prostaglandin) or PGO5 (Kaposi prostaglandin methyl ester) at the vaginal fornix at third or fourth day with the complete abortion rate being as high as 92.3 %. Currently Mifepristone dose has been reduced to a single dose of 200mg, or divided doses of 125-150mg with clinical results not being affected.

The second usage: oral administration of single dose of 600 mg; apply intramuscular injection 0.25 mg of a single oral dose; at 36-48 hours after oral administration, apply intramuscular injection 0.25 mg, or 0.375 mg or 0.5 mg of sulprostone with complete abortion rate of 96%; with the larger amount of sulprostone applied, the sooner the embryonic will be discharged.

The third usage: apply a single oral-administrated dose of 600mg; at 48 hours after oral administration, place 1 mg of ONO802 (gemeprost) pessary suppository inside of the vagina with the complete abortion rate being 95%.


For people with amenorrhea longer than seven weeks, orally administrate 100 mg of mifepristone each time with 2 times per day, and continue for 4 days. You can also apply 1 mg of Kaposi forefront methyl suppository for vagina at 36 to 48 hours after treatment. Have rest in bed for 2 hours and clinic observation for 6 hours. Pay attention to the condition of bleeding after medication to check whether there are pregnancy products being discharged and any adverse reactions. 

For labor induction of middle and late dead fetal, take 200 mg each time and 2 times daily. Consecutively take for two days for inducing menstruation and terminating pregnancy. During the 23 to 26 days at menstrual cycle, take 100~200mg each time with once daily. Consecutively take four days.


Precautions

1. Patients of heart, liver, kidney disease and adrenal insufficiency, hypertension, pregnancy with IUD, suspected ectopic pregnancy are not allowed to apply. 

2. for patients of incomplete abortion or invalid to treatment, they should be treated using vacuum aspiration abortion. Pregnant of over 35 years-old should avoid using it. Patients of allergy are forbidden for using. Follow-up treatment should be performed after 8 to 12 days in order to check the occurrence of complete abortion or stop of bleeding.

3. this d rug can't be combined with rifampin, carbamazepine, griseofulvin, barbiturates, phenytoin, non-steroidal anti-inflammatory d rugs and adrenal hormones.

4. this d rug can't be combined with salicylates, indomethacin, and other analgesics.

5. for people with a long duration of bleeding time, in order to prevent the occurrence of infection, antibiotics and uterotonics should be added. Patients of heart, liver, kidney disease and adrenal insufficiency should be disabled.

6. mifepristone should be kept in darkness and sealed.

7. At 8 to 15 days after taking the d rug, the patients should go to medical center for return visit; when incomplete abortion happens or pregnancy, continues, apply artificial abortion for termination of pregnancy.

The above information is edited by the chemicalbook of Dai xiongfeng.


Chemical Properties

Melting point: 150 °C. [α] D20 + 138.5°(C = 0.5, chloroform). Acute toxicity: mice LD50 (g/kg):> 2.6 with intraperitoneal injection.


Uses It is a novel anti-progestin and has anti-glucocorticoid activity without the activity of progesterone, estrogen, androgen and anti-estrogen. It has a progesterone receptor affinity five times as high as progesterone. It is used for anti-pregnancy, inducing menstruation and terminating pregnancy, intrauterine inducer labor for dead fetal.


Chemical Properties Pale Yellow Solid


Usage

A progesterone receptor antagonist with partial agonist activity. Abortifacient.

glutamate uptake inhibitor, AMPA blocker


Our advantages:

Over 15years specialized in this field,Professional & Experienced sevices provided.

1. Best prices with High quality.We have complete QA&QC system;steroid powder purity is more than 99% hplc. We use the right recipe to cook the injectable steroid oil. All our order will send out after passing the test exam. 

2. Rich experienced in delivering the parcels to you.The most disguise package and the most professional shipping company to ensure safe delivery. . 

3. Enough stock ensure the prompt delivery time.

4. Good after-sales service.

5. Specials are possible when the order is big enough.

6. The most important thing is that we have resend policy to protect you 100%.


Packaging & Delivery:

We have professional team for package and shipment. Special way to ship 100 grams to 100kg powders at one time to your country. Fast and discreet shipment could be arranged for customs pass Guaranteed.


Payment & Shipping Terms:

Minimum Order Quantity:1kg

Price:Negotiable

Packing:1kg/foil bag

Delivery Time: within 24hours after receiving full payment.

Payment terms:T/T,Western Union,MoneyGram.

Supply ability:200kg/month


How to proceed an order: 

1st: Please let me know what you need-Which product/Cas No. quantity, and the destination country. 

2nd: You send us the purchase order once we cme to an agreement on all details. 

3rd: Parcel would be delivered upon full payment received.

4th: Express Tracking No.will be provided about the parcels.

5th: You will get the parcels in 7days.

6th: After-sales service would be provided after you receive parcels.


Should you have any inquires please feel free to contact me ,Skype:live:kathelin_4


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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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