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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Anti-major depressive episodes in adults Raw materials Agomelatine CAS 138112-76-2 manufacturer

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Anti-major depressive episodes in adults Raw materials Agomelatine CAS 138112-76-2 

Price: 1.0 USD 
Payment Terms: T/T,WU,Money Gram 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: Anti-depressive
Production Capacity: 100kgs/month
Delivery Date: within 48hours after receiv...
CAS No.: 138112-76-2
MOQ: 10G
delivery: 24hours after receiving pay...
Usage: bodybuilding
Price: Negociable
Means of Transport: Ocean,Land,Air;Courier Expr...
Packing: discreet pkg
Brand Name: YCGC
Purity: 99%min
Payment: T/T,Western Union,Moneygram...
Pass custom: 99%
User: Adult

Agomelatine is indicated for the treatment of major depressive episodes in adults. primarily for its relatively favorable side effect profile:

Anti-major depressive episodes in adults Raw materials Agomelatine CAS 138112-76-2


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Agomelatine Description:

Agomelatine is indicated for the treatment of major depressive episodes in adults.Ten placebo controlled trials have been performed to investigate the short term efficacy of agomelatine in major depressive disorder. At the end of treatment, significant efficacy was demonstrated in six of the ten short-term double-blind placebo-controlled studies.Two were considered "failed" trials, as comparators of established efficacy failed to differentiate from placebo. Efficacy was also observed in more severely depressed patients in all positive placebo-controlled studies.The maintenance of antidepressant efficacy was demonstrated in a relapse prevention study



Product Name:AGOMELATINE

Synonyms:AGOMELATINE;n-(2-(7-methoxy-1-naphthalenyl)ethyl)-acetamid;n-(2-(7-methoxy-1-naphthalenyl)ethyl)acetamide;n-(2-(7-methoxynaphth-1-yl)ethyl)acetamide;S20098,N-[2-(7-Methoxynaphth-1-yl)ethyl]acetamide;S 20098;AGOMELATIN;Acetamide, N-(2-(7-methoxy-1-naphthalenyl)ethyl)-

CAS:138112-76-2

MF:C15H17NO2

MW:243.30098

Product Categories:Aromatics Compounds;Aromatics;Neurochemicals;APIS;API;Agomelatine;Valdoxan, Melitor, Thymanax

mp :107-109°C

storage temp. :-20°C Freezer

Chemical Properties:White powder

Usage:Agomelatine is an antidepressant drug. It is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor. Activation of 5-HT2C receptors by serotonin inhibits dopamine and norepinephrine release. Antagonism of 



Agomelatine (BAN, rINN; trade names Valdoxan, Melitor, Thymanax) is a melatonergic antidepressant developed by the pharmaceutical company Servier. It is marketed for the treatment of major depressive disorder, primarily for its relatively favorable side effect profile: it avoids the weight gain, sexual dysfunction, and severe withdrawal associated with the most commonly used classes of antidepressants (SSRIs, SNRIs, tricyclics), while providing similar therapeutic benefit.


Due to its distinctive mechanism of action, agomelatine is also studied for its effects on sleep regulation. Studies report various improvements in general quality of sleep metrics, as well as specific therapeutic benefits in circadian rhythm disorders.


Medical uses

Major depressive disorder

Agomelatine is indicated for the treatment of major depressive episodes in adults. Ten placebo controlled trials have been performed to investigate the short term efficacy of agomelatine in major depressive disorder. At the end of treatment, significant efficacy was demonstrated in six of the ten short-term double-blind placebo-controlled studies. Two were considered "failed" trials, as comparators of established efficacy failed to differentiate from placebo. Efficacy was also observed in more severely depressed patients in all positive placebo-controlled studies.The maintenance of antidepressant efficacy was demonstrated in a relapse prevention study. A large meta-analysis of 20 trials with 7460 participants found agomelatine to be as effective as standard antidepressants.


Results of the meta-analysis of three positive, randomized, double-blind, placebo controlled studies in 357 patients treated with agomelatine and 360 patients treated with placebo show that agomelatine is effective in treating severe depression. Its antidepressant effect is greater for more severe depression. In patients with a greater baseline score (>30 on HAMD17 scale), the agomelatine-placebo difference was of 4.53 points. Controlled studies in humans have shown that agomelatine is at least as effective as the SSRI antidepressants paroxetine, sertraline, escitalopram, and fluoxetine in the treatment of major depression.


A small open-label study has suggested efficacy in the treatment of atypical and melancholic depression.Well-designed clinical trials have demonstrated efficacy in the treatment of anxious depression.




Our advantages:

Over 15years specialized in this field,Professional & Experienced sevices provided.

1. Best prices with High quality.We have complete QA&QC system;steroid powder purity is more than 99% hplc. We use the right recipe to cook the injectable steroid oil. All our order will send out after passing the test exam. 

2. Rich experienced in delivering the parcels to you.The most disguise package and the most professional shipping company to ensure safe delivery. . 

3. Enough stock ensure the prompt delivery time.

4. Good after-sales service.

5. Specials are possible when the order is big enough.

6. The most important thing is that we have resend policy to protect you 100%.


Packaging & Delivery:

We have professional team for package and shipment. Special way to ship 100 grams to 100kg powders at one time to your country. Fast and discreet shipment could be arranged for customs pass Guaranteed.

Payment & Shipping Terms:

Minimum Order Quantity:25KG (25KG/Drum

Price:Negotiable

Packing:25kg/drum or as required

Delivery Time: within 24hours after receiving full payment.

Payment terms:T/T,Western Union,MoneyGram.

Supply ability:200kg/month


How to proceed an order: 

1st: Please let me know what you need-Which product/Cas No. quantity, and the destination country. 

2nd: You send us the purchase order once we cme to an agreement on all details. 

3rd: Parcel would be delivered upon full payment received.

4th: Express Tracking No.will be provided about the parcels.

5th: You will get the parcels in 7days.

6th: After-sales service would be provided after you receive parcels.


Should you have any inquires please feel free to contact me ,kathelin(at) yccreate(doc)com.


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Tel: 86-27-88211875
Mobile: 188 7222 0799
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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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