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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Ending Pregnancy Misoprostol Mifepristone powder manufacturer

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Ending Pregnancy Misoprostol Mifepristone powder 

Price: 85.0 USD 
Payment Terms: T/T,WU,Money Gram;Bitcoin 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: 59122-46-2
Production Capacity: 500kg/month
Delivery Date: 3-15days
CAS No.: 84371-65-3
Alias: Mifepristone
usage: Anti-Pregnancy
Main ingredient: Misoprostol
appearance: white powder.
price: negotiable
Means of Transport: Ocean,Air;Express(DHL/UPS/F...
Packing: disguise package or as requ...
Brand Name: Gongchuang
Purity: 99%
source: Mifepristone price
application: Ending Pregnancy
Standard: USP/BP
effect: Misoprostol

1,Misoprostol is a synthetic (man-made) prostaglandin;
2,Misoprostol is used to reduce the risk of stomach ulcer
3.Misoprostol is a synthetic steroi

High Purity Prohormones Steroids Misoprostol For Antiulcerative CAS 59122-46-2

Misoprostol
Misoprostol CAS: 59122-46-2
Misoprostol MF: C22H38O5
Misoprostol MW: 382.54
Misoprostol Chemical Properties White Solid
Misoprostol Usage antiulcerative;prostaglandin E1 analog that inhibits gastric acid secretion
Usage A cytoprotective prostaglandin PGE1 analogue
Biological Activity Cytoprotective prostaglandin E 1 analog that displays agonist activity at EP receptors. K i values are 120, 250, 67 and 67 nM at cloned mouse EP 1 , EP 2 , EP 3 and EP 4 receptors respectively. Prevents NSAID-induced gastric ulceration.

Misoprostol Description:
Misoprostol (brand name Cytotec) is a prostaglandin. Misoprostol is a synthetic (man-made) prostaglandin that is used to reduce the risk of stomach ulcers in patients treated with nonsteroidal antiinflammatory drugs (NSAIDs, for example,aspirin, ibuprofen, etc.) that are used for pain and various inflammatory conditions, for example, arthritis. Misoprostol is used primarily in patients at high risk for stomach ulcers when treated with NSAIDs, for example, the elderly, patients with concomitant debilitating diseases, and patients with a history of ulcers. Prostaglandins are chemicals that are made within many organs of the body including the stomach. In the stomach, prostaglandins are believed to protect the inner lining of the stomach from the ulcer-producing effects of NSAIDs. Misoprostol is also used sometimes to treat ulcers and to induce labor. Misoprostol is used in combination with mifepristone to end an early pregnancy. Talk to your doctor about the possible risks of using this drug for your condition.

Misoprostol Application:
Misoprostol is a prostaglandin analog that is registered in over 60 countries for treatment and prevention of gastric ulcers caused by prolonged use of anti-inflammatory medications. Because misoprostol causes uterine contractions, it is useful for a variety of obstetric and gynecologic purposes.
Misoprostol is the generic form of the brand-name drug Cytotec, which is used to prevent ulcers in people who take certain arthritis or pain medicines. Misoprostol is a synthetic prostaglandin. It works by protecting the stomach lining and decreasing stomach acid secretion. Misoprostol is sometimes used off-label to end an early pregnancy. The drug is most effective when it's used in combination with or mifepristone. Misoprostol can be given orally, buccally (dissolved between the gums and cheek), or vaginally for this purpose.Misoprostol tablets will replace your natural prostaglandins so you can continue getting benefit from your NSAID painkiller. If you already have an ulcer, misoprostol will help it to heal.


New Anti-Progesterone Mifepristone CAS 84371-65-3 for Contraception

Mifepristone
Synonyms: Estra-4, 9-dien-3-one, 11-[4-(dimethylamino)- phenyl]-17-hydroxy-17-(1-propynyl)-, (11a, - 17a)-Mifepristone; 17-beta-Hydroxy-11-beta-(4-dimethylaminophenyl-1)-17-alpha-(prop-1-ynyl)oestra-4, 9-dien-3-one
Inchi: InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26, 29)2)19-6-9-21(10-7-19)30(3)4/h6-7, 9-10, 17, 24-26, 32H, 8, 11-14, 16, 18H2, 1-4H3/t24-, 25+, 26-, 28-, 29-/m0/s1
Mifepristone CAS No.: 84371-65-3
Mifepristone MF: C29H35NO2
Mifepristone MW: 429.59
Mifepristone Purity: 99%min
Mifepristone Density: 1.18 g/cm3
Mifepristone Melting Point: 195-198° C
Mifepristone Boiling Point: 628.6 ° C at 760 mmHg
Mifepristone Refractive Index: 1.623
Mifepristone Flash Point: 334 ° C
Mifepristone Appearance: Pale Yellow Solid
Mifepristone Grade: Pharmaceutical Grade
Storage: Shading, confined preservation
Lead time: Within 12 hours upon receipt of payment
Delivery: EMS, DHL, TNT, FedEx, UPS
Usage: New anti-progesterone, and has anti-glucocorticoid activity, but not progesterone, estrogen, androgen and anti-estrogen activity. And progesterone receptor affinity 5-fold stronger than progesterone. For anti-early pregnancy, reminders by only pregnancy, fetal death, uterine induction of labor, etc.

Product description:
Mifepristone (or RU-486) is a synthetic steroid compound with both antiprogesterone and antiglucocorticoid properties. The compound is a 19-nor steroid with substitutions at positions C11 and C17 (17 beta-hydroxy-11 beta-[4-dimethylamino phenyl] 17 alpha-[1-propynyl]estra-4, 9-dien-3-one), which antagonizes cortisol action competitively at the receptor level.
Mifepristone is a progesterone receptor antagonist used as an abortifacient in the first months of pregnancy, and in smaller doses as an emergency contraceptive. It is also a powerful glucocorticoid receptor antagonist, and has occasionally been used in refractory Cushing's syndrome (due to ectopic/neoplastic ACTH/cortisol secretion).
Mifepristone was the first antiprogestin to be developed and it has been evaluated extensively for its use as an abortifacient.

Mifepristone Application:
Mifepristone can also be used in smaller doses as an emergency contraceptive; If taken after sex but before ovulation, it can prevent ovulation and so prevent pregnancy. In this role, a 10-mg dose is not as effective as the 600-mg dose, but has fewer side effects. Mifeprex and Mifegyne are only available in 200-mg tablets.
A review of studies in humans found that the contraceptive effects of the 10-mg dose were probably due mainly to its effects on ovulation, and not inhibition of implantation, but "the knowledge of the mechanism of action remains incomplete". Treatment with 200 mg of mifepristone changes steroid receptor expression in the Fallopian tube, inhibits endometrial development, and effectively prevents implantation.
Other medical applications of mifepristone studied in clinical trials include regular long-term use as an oral contraceptive, and treatment of HIV infection, uterine fibroids, endometriosis, major depression with psychotic features, bipolar depression and disorders causing cognitive dysfunction, post-traumatic stress disorder, chronic multisymptom illness, glaucoma, meningiomas, breast cancer, ovarian cancer, and prostate cancer.


Specification:

Items of analysisSpecificationResults
DescriptionLight Yellowish Crystalline PowderLight Yellowish Crystalline Powder
Identificationthe maximum absorption wavelength of 304nm, 260nm, and infrared absorption spectra were consistent with the control product.Conformity
Melting Point192ºC~196ºC
192ºC~196ºC
192ºC~196ºC
192ºC~196ºC
Specific Rotation+124°~ +129°
+124°~ +129°
+127.3°
+127.3°
Single Impurity≤0.5%
≤0.5%
0.45%
0.45%
Total Impurity≤1.0%
≤1.0%
0.60%
0.60%
Loss On Drying≤0.5%
≤0.5%
0.2%
0.2%
Assay≥98.5%
≥98.5%
99.4%
99.4%
Sieve analysis≤30μm
≤30μm
Conformity
ConclusionQualified


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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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