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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Corticosteroids Pharmaceutical Intermediate CAS 378-44-9 Betamethasone manufacturer

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Corticosteroids Pharmaceutical Intermediate CAS 378-44-9 Betamethasone 

Price: 1.0 USD 
Payment Terms: T/T,WU,Money Gram;BItcoin 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: pharm raw material
Production Capacity: 5000kg per month
Delivery Date: within 24 hours after payme...
CAS No.: 378-44-9
Betamethasone color: white
Betamethasone Alias: Betamethasone
Betamethasone EINECS: 206-825-4
Betamethasone payment methods: T/T, Westeron Union, Money ...
Betamethasone Standard: Enterprise Standard
Means of Transport: Air;express
Packing: disguised package
Brand Name: Betamethasone
Purity: 99%
Betamethasone appearence: powder
Betamethasone MF: C22H29FO5
Betamethasone package: safe discreet package
Betamethasone lead time: within 24hour after payment...
Betamethasone Delivery time: 5-7 days

Betamethasone is mainly used for anti-inflammatory and allergy
Betamethasone is a corticosteroid used as a topical cream
Betamethasone safe shipping


Anti-Inflammatory Glucocorticoid Steroids Powder CAS 378-44-9 Betamethasone

Corticosteroids Pharmaceutical Intermediate CAS 378-44-9 Betamethasone


Betamethasone Base Basic information


Product name: Betamethasone Base

CAS: 378-44-9

EINECS: 206-825-4

Quality standard: Cp2005

MF: C22H29FO5

MW: 392.4611

Density: 1.32g/cm3

Melting point: 235-237º C

Boiling point: 568.2º C at 760 mmHg

Flash point: 297.5º C

Refractive index: 118 ° (C=1, Dioxane)

Vapour pressure: 2.81E-15mmHg at 25º C

Usage: Hormonal drugs.

USES: Anti-inflammatory, allergy, relieving itching and reduce the role; Many used in the treatment of active rheumatism, rheumatoid arthritis, lupus erythematosus, serious bronchus asthma, serious dermatitis, acute leukemia, etc, and also in some infection treatment.



Betamethasone Description: 


Betamethasone is a potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties. Unlike other drugs with these effects, betamethasone does not cause water retention. It is applied as a topical cream, ointment, foam, lotion or gel to treat itching. Betamethasone sodium phosphate is sometimes prescribed as an intramuscular injection (I. M) for itching from various ailments, including allergic reactions to poison ivy and similar plants. 

 

Betamethasone sugar metabolism and hydrocortisone anti-inflammatory effect is strong, 15 times for hydrocortisone, but sodium retention effect of hydrocortisone more than one hundred times, in the primary adrenocortical hypofunction, could be used for alternative treatment with glucocorticoid steroid. Also apply to low renin aldosterone syndrome and orthostatic hypotension caused by plant nerve lesions, etc.


Betamethasone Application


1. Betamethasone is mainly used for anti-inflammatory and allergy. Applicable to rheumatoid arthritis, and all sorts of skin diseases. The effect of betamethasone and dexamethasone, its anti-inflammatory effects than dexamethasone, loose to inflammation and hydrocortisone is strong, less side effects.

2. Betamethasone is a corticosteroid used as a topical cream to relieve skin irritation, such as itching and flaking from eczema. It is used as a treatment for local psoriasis, as betamethasone dipropionate and salicylic acid, or as the combination betamethasone/calcipotriol. Betamethasone sodium phosphate is used orally and via injection with the same indications as other steroids. 

3. Betamethasone is also used prior to delivery of a preterm baby to help prepare the lung for breathing 

4. In a randomized controlled trial Betamethasone was shown to reduce some of the ataxia symptoms associated with Ataxia Telangiectasia (A-T) by 28-31%.




Betamethasone Specification





Item of AnalysisSpecificationResults
AppearanceWhite or almost white crystalline powderComplies
SolubilityPractically insoluble in waterComplies
Identification (B,C)Complies with the StandardComplies
Specific optical Rotation+118°~+126°+123.6°
Single impurityNot more than 1.0%0.36%
impurity that ≥0.5%Not more than oneComplies
total impuritiesNot more than 2.0%0.84%
Loss on dryingNot more than 1.0%0.10%
Assay(UV, basis on drying)97.0%~103.0%99.80%
MethanolNot more than 3000ppmComplies
Ethyl acetateNot more than 5000ppmComplies
AcetoneNot more than 5000ppmComplies
DMFNot more than 880ppmComplies
DichloromethaneNot more than 600ppmComplies
ChloroformNot more than 60ppmComplies
Particle Size90%<10umComplies
ConclusionQualified



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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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