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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China 99% nootropic Donepezil Powder for Alzheimer′s Disease CAS 120014-06-4 manufacturer

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99% nootropic Donepezil Powder for Alzheimer′s Disease CAS 120014-06-4 

Price: 90.0 USD 
Payment Terms: T/T,D/A,WU,Money Gram;Bitcoin 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: nootropic raw
Production Capacity: 500kg//month
Delivery Date: 4-15days
CAS No.: 120014-06-4
Alias: Donepezil for sale
manufacturer: Donepezil factory
price: bulk price
effects: medical raw
package: as require
Means of Transport: Ocean,Air;Express
Packing: disguise package or as requ...
Brand Name: gongchuang
Purity: 99%
source: Donepezil source
quality: guranteed
supplier: +8618872220799
purity: 99%min
Standard: USP/BP/USP Anpp

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Donepezil powder for sale; Donepezil for Alzheimer′s Disease
Donepezil raw chemical

99% Donepezil Powder for Alzheimer′s Disease

99% Donepezil Powder for Alzheimer′s Disease CAS 120014-06-4


99% Donepezil powder for Alzheimer's disease 

Donepezil Molecular Formula:C24H29NO3

Donepezil Formula Weight:379.49

Donepezil CAS No.:120014-06-4

Donepezil Purity:99%

Donepezil Appearance:white powder


Donepezil Base

Donepezil is a centrally acting reversible acetylcholinesterase inhibitor. Its main therapeutic use is in the palliative treatment of Alzheimer's disease. Common side effects include gastrointestinal upset. It has an oral bioavailability of 100% and easily crosses the blood-brain barrier. Because it has a biological half-life of about 70 hours, it can be taken once a day.


Donepezil has been tested in other cognitive disorders (and is sometimes used off label) including Lewy body dementia and vascular dementia, but it is not currently approved for these indications. Donepezil has been found to improve sleep apnea in Alzheimer's patients. Donepezil has also been studied in patients with Mild Cognitive Impairment, schizophrenia, attention deficit disorder, post-coronary bypass cognitive impairment, cognitive impairment associated with multiple sclerosis, CADASIL, and Down syndrome. A 3 year NIH trial in patients with mild cognitive impairment reported that donepezil was superior to placebo in delaying rate of progression to dementia during the initial 18 months of the study but this was not sustained at 36 months. In a secondary analysis, a subgroup of individuals with the Apolipoprotein E4 genotype showed sustained benefits with donepezil throughout the study. However at this time donepezil is not indicated for prevention of dementia. Recent studies suggest that Donepezil can improve speech in children with autism. The studies found that speech of autistic children who were mild to moderately affected appeared to improve from the use of Donepezil.

The COA:

TEST ITEM SPECIFICATIONRESULT
AppearanceOff white to white crystalline powderComplies
Solubilityfreely  Freely soluble in chloroform, soluble
 in water and Acetic acid, slightly soluble in
 Acetonitrile  and ethanol, insoluble in
 Ethylacetoacetate and  n-hexane
Complies
Identification(1)By IR absorption ,To match with working
 standard
Complies
(2) The retention time of the major peak of
 the sample should  accord with that of the
 working standard.
Complies
 
(3) Test for chlorides. Reponds to the test
 for Chlorides.
Complies
 
PH 4.0-7.06.10
Residue on ignition≤0.1%0.03%
Related substance Any Unkonwn single impurity≤0.3%
Total ≤0.5%
0.04% 
0.18%
Heavy metal  ≤10ppm<10ppm
Residual SolventsMethanol≤0.3%
Ethanol≤0.5%
Ethyl acetate≤0.5%
Toluene≤0.089%
Acetic acid≤0.5%
Not detected
Not detected
Not detected
Not detected
Not detected
Loss on drying≤0.5%0.20%
AssayOn dried base, C24H29NO3·HCl
 should be 98.0% to 102.0%
100.20%
Conclusion: The product complies to Enterprise standard


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Tel: 86-27-88211875
Mobile: 188 7222 0799
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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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