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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Hormone Powder Female Sex Enhancer Flibanserin Hydrochloride Flibanserin HCL CAS 147359-76-0 manufacturer

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Hormone Powder Female Sex Enhancer Flibanserin Hydrochloride Flibanserin HCL CAS 147359-76-0 

Price: 1.0 USD 
Payment Terms: T/T,WU,Money Gram 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: ANTI-DEPRESSION
Production Capacity: 500kgs/month
Delivery Date: within 48hours after receiv...
CAS No.: 147359-76-0
Apperance: liquid
MOQ: 100ml
user: adult
Means of Transport: Ocean,Land,Air;Courier Expr...
Packing: disguised
Brand Name: YCGC
Purity: 99.5%
Payment: T/T,West Union,Money Gram,e...
Usage: ANTI-DEPRESSION
Price: change according to the mar...

Hormone Powder Female Sex Enhancer Flibanserin Hydrochloride Flibanserin HCL CAS 147359-76-0 anti-depression
Chemical name: Flibanserin Hydrochloride

Hormone Powder Female Sex Enhancer Flibanserin Hydrochloride Flibanserin HCL CAS 147359-76-0 anti-depression


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Flibanserin is a medication approved for the treatment of pre-menopausal women with hypoactive sexual desire disorder (HSDD).The medication increases the number of satisfying sexual events per month by about one half over placebo from a starting point of about two to three.The certainty of the estimate is low.The side effects of dizziness, sleepiness, and nausea occur about three to four times more often.


Development by Boehringer Ingelheim was halted in October 2010 following a negative evaluation by the U.S. Food and Drug Administration.The rights to the drug were then transferred to Sprout Pharmaceuticals, which achieved approval of the drug by the US FDA in August 2015.


HSDD was recognized as a distinct sexual function disorder for more than 30 years, but was removed from the Diagnostic and Statistical Manual of Mental Disorders in 2013, and replaced with a new diagnosis called female sexual interest/arousal disorder (FSIAD).

Chemical name: Flibanserin Hydrochloride

Synonyms: BIMT 17 Hydrochloride; BIMT 17BS Hydrochloride; 1-(2-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)ethyl)-1H-benzo[d]imidazol-2(3H)-one Hydrochloride

Impurity:

CAS Number: 147359-76-0

Possible CAS #: NA

Molecular form.: C₂₀H₂₂ClF₃N₄O

Appearance: White Solid

Melting Point: >225°C (dec.)

Mol. Weight: 426.86

Storage: Room Temperature

Solubility: DMSO, Methanol

Stability: No Data Available

Category: Agonist, Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals

Applications: Flibanserin is a 5-HT1A agonist and 5-HT2A antagonist that is developed for the treatment of hypoactive sexual desire disorder in women (1,2).

Dangerous Goods Info: NA


Medical uses

Flibanserin is used for hypoactive sexual desire disorder among women. Those receiving flibanserin report a 0.5 increase compared to placebo in the number of times they had "satisfying sexual events". In those on flibanserin it rose from 2.8 to 4.5 times a month while women receiving placebo reported also an increase of "satisfying sexual events" from 2.7 to 3.7 times a month.The onset of the flibanserin effect was seen from the first timepoint measured after 4 weeks of treatment and maintained throughout the treatment period.


The effectiveness of flibanserin was evaluated in three phase 3 clinical trials. Each of the three trials had two co-primary endpoints, one for satisfying sexual events (SSEs) and the other for sexual desire. Each of the 3 trials also had a secondary endpoint that measured distress related to sexual desire. All three trials showed that flibanserin produced an increase in the number of SSEs and reduced distress related to sexual desire. The first two trials used an electronic diary to measure sexual desire, and did not find an increase. These two trials also measured sexual desire using the Female Sexual Function index (FSFI) as a secondary endpoint, and an increase was observed using this latter measure. The FSFI was used as the co-primary endpoint for sexual desire in the third trial, and again showed a statistically significant increase.


Women's overall feeling of improvement was small to none. The overall quality of the evidence was low.


Side effects

Adverse events are more common among women taking flibanserin. The majority of adverse events were mild to moderate. The most commonly reported adverse events included dizziness, nausea, feeling tired, sleepiness, and trouble sleeping.


Drinking alcohol while on flibanserin may result in severely low blood pressure (low blood pressure that produced symptoms occurred after only 2 glasses of wine occurred in 17%).


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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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