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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Nootropic Chemical Powder Supplement Noopept Idra-21 for Brain Idra 21 manufacturer

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Nootropic Chemical Powder Supplement Noopept Idra-21 for Brain Idra 21 

Price: 90.0 USD 
Payment Terms: T/T,D/A,WU,Money Gram;Bitcoin 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: ampakine drug
Production Capacity: 500kg//month
Delivery Date: 4-15days
CAS No.: 22503-72-6
Alias: IDRA 21 for sale
manufacturer: IDRA 21 factory
price: bulk price
effects: medical raw
package: as require
Means of Transport: Ocean,Air;Express
Packing: disguise package or as requ...
Brand Name: gongchuang
Purity: 99%
source: IDRA 21 source
quality: guranteed
supplier: +8618872220799
purity: 99%min
Standard: USP/BP/USP Anpp

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IDRA 21

Nootropic Supplement Smart Drug Idra 21 for Memory Improvement Idra-21 

Nootropic Chemical Powder Supplement Noopept Idra-21 for Brain Idra 21 

Identification

Name

7-Chloro-3,4-dihydro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide

Synonyms IDRA 21

Solubility: Sparingly Soluble (0.93 g/L) (25 ºC), Calc.*

Idra-21 Molecular Formula C8H9ClN2O2S

Idra-21 Molecular Weight 232.69

Idra-21 CAS Registry Number 22503-72-6

Idra-21 Storage Store at room temperature

Properties

Melting point 209 ºC (acetic acid )**

 

Introduction  

IDRA-21 is an ampakine drug and a benzothiadiazine derivative. IDRA-21 is a chiral molecule, with (+)-IDRA-21 being the active form.

IDRA-21 shows nootropic effects in animal studies, significantly improving learning and memory. It is around 10-30 times more potent than aniracetam in reversing cognitive deficits, and produces sustained effects lasting for up to 48 hours after a single dose. The mechanism for this action is thought to be through promoting the induction of long-term potentiation between synapses in the brain.

IDRA-21 does not produce neurotoxicity under normal conditions, although it may worsen neuronal damage following global ischemia after stroke or seizures.

In comparison to the benzoylpiperidine derived ampakine drug, IDRA-21 was more potent than CX-516, but less potent than CX-546.[8] Newer benzothiadiazide derivatives with greatly increased potency compared to IDRA-21 have been developed,but these have not been researched to the same extent, with the benzoylpiperidine and benzoylpyrrolidine CX-series of drug being favoured for clinical development, most likely due to more favourable toxicity profiles at high doses.


In comparison to the benzoylpiperidine derived ampakine drug, IDRA-21 was more potent than CX-516, but less potent than CX-546. Newer benzothiadiazide derivatives with greatly increased potency compared to IDRA-21 have been developed, but these have not been researched to the same extent, with the benzoylpiperidine and benzoylpyrrolidine CX-series of drug being favoured for clinical development, most likely due to more favourable toxicity profiles at high doses.


IDRA-21 Benefits


1. Increase in cognition.

2. Increase Task Accuracy

3. Increases in Short Term Memory

4. Potential Therapeutic Effects On Schizophrenia

5. Potental Therapeutic Effects On Depression

6. Neuroprotection


IDRA-21 Mechanism Of Action

As an Ampakine, IDRA-21 works by modulating AMPA receptors in the brain. it may prevent AMPA receptor desensitization, specifically IDRA-21 binds to the allosteric site of the AMPA receptor and induce positive modulation, this is sometimes called allosteric activation.

This property enhances long-term potentiation, especially within the hippocampus and may thus have beneficial therapeutic effects. This research could imply that IDRA-21 facilitates treatment of AMPA-related learning disabilities or enhancing intelligence in those without any learning disabilities.

In animal studies, IDRA-21 showed extremely long-lasting nootropic effects in improved learning and memory for up to 48 hours with a single dose. IDRA-21 showed to be up to ten times more powerful than the similar supplement aniracetam.


IDRA-21 Safety and Side Effects

IDRA-21 is a potent Ampakine. AMPA activation has been shown to exacerbate hippocampal neural damage. IDRA-21 when administered with glutamate killed rat hippocampal neurons through AMPA excitoxicity. This is potentially dangerous in patients with conditions that excessively activate AMPA such as strokes and seizures.


In another study, the dosages of IDRA-21 that induced neurotoxicity were several orders of magnitude higher than the doses that achieved cognitive enhancement in rats and monkeys, leading the researchers to conclude that IDRA-21 has relatively low neurotoxicity in therapeutic doses.


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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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