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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China CAS:28721-07-5 Oxcarbazepine powder for anticonvulsant and treatment of epilepsy manufacturer

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CAS:28721-07-5 Oxcarbazepine powder for anticonvulsant and treatment of epilepsy 

Price: 1.0 USD 
Payment Terms: T/T,WU,Money Gram 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: anti-convulsant
Production Capacity: 500kgs/month
Delivery Date: within 48hours after receiv...
CAS No.: 28721-07-5
Apperance: POWDER
MOQ: 10G
Price: change according to the mar...
Means of Transport: Ocean,Land,Air;Courier Expr...
Packing: disguised
Brand Name: YCGC
Purity: 99%
Payment: T/T,West Union,Money Gram,e...
Usage: anticonvulsant
user: adult

Oxcarbazepine is an anticonvulsant drug primarily used in the treatment of epilepsy.
and used as add-on therapy for bipolar disorder in patients

CAS:28721-07-5 Oxcarbazepine powder for anticonvulsant and treatment of epilepsy


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Oxcarbazepine

Oxcarbazepine is an anticonvulsant drug primarily used in the treatment of epilepsy. There is some evidence for oxcarbazepine as a mood-stabilizing agent and thus, it can be used as add-on therapy for bipolar disorder in patients that have failed or are unable to tolerate approved treatments.


Common side effects include nausea, vomiting, dizziness, drowsiness, headache, double vision and trouble with walking.Although not common, anaphylaxis may occur.Due to its structural similarities to carbamazepine there is approximately a 25–30% chance of cross-reactivity between the two medications.


Oxcarbazepine is marketed as Trileptal by Novartis and available in some countries as a generic drug.There is also an extended-release formulation marketed as Oxtellar XR by Supernus Pharmaceuticals.

Product Name:Oxcarbazepine

Synonyms:10,11-DIHYDRO-10-OXO-5H-DIBENZ[B,F]AZEPINE-5-CARBOXAMIDE;10,11-DIHDYRO-10-OXO-5H-DIBENZ[B,F]AZEPINE-5-CARBOXAMIDE;5H-DIBENZ[B,F]AZEPINE-5-CARBOXAMIDE, 10,11-DIHYDRO-10-OXO-;TRILEPTAL;f)azepine-5-carboxamide,10,11-dihydro-10-oxo-5h-dibenz(;gp47680;OXCARBAMAZEPINE;OXCARBAZEPINE

CAS:28721-07-5

MF:C15H12N2O2

MW:252.27

EINECS:249-188-8

Product Categories:Heterocyclic Compounds;APIs;Intermediates & Fine Chemicals;Pharmaceuticals;Chiral Reagents;Heterocycles;Metabolites & Impurities;Pharmaceutical raw material;Chiral Reagents, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;COREG;Other APIs

Melting point:215-216°C

storage temp.: Store at RT

solubility:DMSO: ~9 mg/mL

form:solid

color:white

Water Solubility:Soluble in DMSO, methanol, water, ethanol and acetone.

Chemical Properties:Pale Yellow Powder

Uses:A metabolite of Eslicarbazepine acetate, (BIA 2-093), a novel central nervous system drug.

Uses:beta-adrenergic blocker

Uses:The keto derivative of Carbamazepine. Used as an anticonvulsant


Medical uses

Oxcarbazepine is an anticonvulsant used to reduce the occurrence of epileptic episodes, and is not intended to cure epilepsy.Oxcarbazepine is used alone or in combination with other medications for the treatment of focal (partial) seizures in adults.In pediatric populations, it can be used by itself for the treatment of partial seizures for children 4 years and older, or in combination with other medications for children 2 years and older.


In addition, oxcarbazepine has been shown to improve mood and reduce anxiety; therefore, it is a potential option for add-on therapy in the treatment of bipolar disorder.



Side effects

The most common side effects associated with oxcarbazepine include:

dizziness (6.4%)

blurred or double vision (2.1%)

fatigue (2.1%)

headaches (2.9%)

nausea (4.9%)

vomiting (2%)

sleepiness (2.4%)

there is evidence of difficulty in concentration and mental sluggishness

Other rare side effects of oxcarbazepine include:


severe low blood sodium (1%)

anaphylaxis / angioedema

hypersensitivity (especially if experienced with carbamazepine previously [25-30% cross-reactivity])

toxic epidermal necrolysis (TEN, 0.5 to 6 cases per million-person years)

Stevens–Johnson syndrome (SJS, 0.5 to 6 cases per million-person years)

thoughts of suicide (<1%)

Serum sodium levels should be considered in maintenance treatment or symptoms of hyponatremia develop.Some side effects (such as headache) are more pronounced shortly after a dose is taken and tend to fade with the passage of time (60 to 90 minutes). Other side effects include stomach pain, tremor, rash, diarrhea, constipation, decreased appetite and dry mouth. Photosensitivity is a potential side-effect and people could experience severe sunburns as a result of sun exposure.


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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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