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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Good Quality Anti Inflammatory Pharma Raw Powder Azelastine Hydrochloride manufacturer

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Good Quality Anti Inflammatory Pharma Raw Powder Azelastine Hydrochloride 

Price: 1.0 USD 
Payment Terms: T/T,WU,Money Gram;BItcoin 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: pharma raw powder
Production Capacity: 5000kg per month
Delivery Date: within 24 hours after payme...
CAS No.: 79307-93-0
Azelastine hydrochloride Color: white
Azelastine hydrochloride Alias: azeptin, AZELASTINE HCL
Azelastine hydrochloride Usage: Antihistaminic
Azelastine hydrochloride Standard: Enterprise Standard
Azelastine hydrochloride Delivery time: 5-7 days
Means of Transport: Ocean,Air;Express
Packing: disguised package
Brand Name: Azelastine hydrochloride
Purity: 99%
Azelastine hydrochloride appearence: crystalline powder
Azelastine hydrochloride Molecular Formula: C22H25Cl2N3O
Azelastine hydrochloride MOQ: 100gams
Azelastine hydrochloride Lead time: within 24hours after paymen...
Azelastine hydrochloride shipping methods: ship by HKEMS,DHL,TNT, FEDE...

Azelastine is a potent histamine antagonist agent
Azelastine hydrochloride is used to antihistaminic
both adults and children can use Azelastine HCL

Antihistaminic Pharmaceutical Raw Materials Azelastine Hydrochloride

Good Quality Anti Inflammatory Pharma Raw Powder Azelastine Hydrochloride


Product Name: Azelastine hydrochloride 

Synonyms: a5610;azeptin;e-0659;w-2979m;AZELASTINE HCL;AZELASTINE HYDROCHLORIDE;4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-phthalazin-1-one hydrochloride;4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1(2H)-phthalazinone Hydrochloride 

CAS: 79307-93-0 

MF: C22H25Cl2N3O 

MW: 418.36

Product Categories: Antihistaminic;Intermediates & Fine Chemicals;Pharmaceuticals;Histamine receptor;Astelin

Melting point  225--229ºC

Storage temp.  -20°C Freezer 

Stability: Incompatible with strong oxidizing agents. 

Chemical Properties White Crystalline Powder 

Usage Orally active H1-hystamine receptor antagonist. Antihistaminic .



Azelastine hydrochloride Description:

 

Azelastine is a potent, second-generation, selective, histamine antagonist (histamine-H1-receptor antagonist) used as a first line therapy of mild intermittent, moderate/severe intermittent and mild persistent rhinitis (new classification system for rhinitis).


Azelastine has been formulated both as a nasal spray and as eye drops and are available worldwide under many brand names.


Azelastine hydrochloride Application:

 

This medication is used to treat itching eyes caused by allergies (allergic conjunctivitis). Azelastine belongs to a class of drug known as antihistamines. It works by blocking certain natural substances called histamines that are responsible for allergic symptoms.

 

Azelastine nasal spray is indicated for the local treatment of the symptoms of seasonal allergic rhinitis and perennial allergic rhinitis, such as rhinorrhea, sneezing and nasal pruritus in adults and children 5 years of age and older. In some countries, it is also indicated for the treatment of vasomotor rhinitis in adults and children ≥ 12 years old. Azelastine eyes drops are indicated for the local treatment of seasonal and perennial allergic conjunctivitis.Uses for Azelastine HydrochlorideSeasonal Allergic RhinitisSymptomatic treatment of seasonal allergic rhinitis (e.g., hay fever). Intranasal azelastine is at least as effective as oral antihistamines (e.g., cetirizine) or intranasal corticosteroids.May provide improvement of ocular manifestations, possibly secondary to systemic absorption of the drug.Nonallergic RhinitisSymptomatic treatment of nonallergic (vasomotor) rhinitis;Allergic ConjunctivitisSymptomatic relief of ocular itching associated with allergic conjunctivitis.


Azelastine hydrochloride Dosage:


Available as azelastine hydrochloride; dosage expressed in terms of the salt.1

When properly primed, the nasal spray pump delivers approximately 100 metered doses per bottle.Pediatric PatientsSeasonal Allergic RhinitisIntranasalChildren ≥12 years of age: 2 sprays (274 mcg) in each nostril twice daily.


Children 5-11 years of age: 1 spray (137 mcg) in each nostril twice daily.Nonallergic RhinitisIntranasalChildren ≥12 years of age: 2 sprays (274 mcg) in each nostril twice daily.Allergic ConjunctivitisOphthalmicChildren ≥3 years of age: 1 drop of a 0.05% solution in the affected eye(s) twice daily.AdultsSeasonal Allergic RhinitisIntranasal2 sprays (274 mcg) in each nostril twice daily.Nonallergic RhinitisIntranasal2 sprays (274 mcg) in each nostril twice daily.Allergic ConjunctivitisOphthalmic1 drop of a 0.05% solution in the affected eye(s) twice daily.


Azelastine hydrochloride Side Effect:


Azelastine is safe and well tolerated in both adults and children with allergic rhinitis. Bitter taste, headache, nasal burning and somnolence are the most frequently reported adverse events. US prescribing recommendations warn against the concurrent use of alcohol and/or other central nervous system depressants, but to date there have been no studies to assess the effects of azelastine nasal spray on the CNS in humans.


More recent studies have shown similar degrees of somnolence (approx. 2%) compared with placebo treatment. The problem of bitter taste may be reduced by correct application of the nasal spray (i.e. slightly tipping the head forward and not inhaling the medication too deeply), or alternatively using the azelastine/sucralose formulation.


Azelastine hydrochloride Specification


Results of Analysis Tests

Test Items

Specification

Results of Analysis

Appearance

White crystalline powder

White crystalline powder

Identificantion

IR/H-NMR 

Conforms

Heavy mental

≤10ppm

Conforms

Solubility 

Sparingly soluble in water, soluble in ethanol and in methylene chloride.

Conforms

Loss on drying 

≤0.5%

0.12%

Burned ash

≤0.1% 

0.05%

Single impurity 

≤0.1% 

0.04%

Total Impurities

≤0.2%

0.07%

Purity

≥99.0%

99.93%

Storage

Containers Well-closed containers Storage Light-resistant

Containers Well-closed containers Storage Light-resistant

Conclusion

The specification comply with Enterprise Standard


About US


We always willing to make a better deal for you. For regular customers we are giving great offers.

Oncce one become our customer, he will definitely return for another order.


Our mission is to provide our customer with an excellent personal service which develops long-term relationship, meeting their specific needs within budget and time frame. Ensure regulatory compliance are maximize on clients core competencies and product quality through optimized validated and controlled processes.


We have customer desired packing methods chosen and recommended by most of our customers.

We do pack as the customer desires the package to be packed....


All products are produced under GMP conditions according to Standard Operation Procedure(SOP), 

not from little underground labs or black markets, so the quality is guaranteed.


Prices depends on your order but we always encourage new clients to place sample / small orders and check our service, 

products and our communication and then gradually do your regular business with us. Of course bulk orders will enjoy discounts.


All products are bulk in stock, usually ship within 24-48 hours of your order being received and processed. Fast Express Delivery ,Available with UPS,FedEx,EMS,DHL,TNT and so on, 

secure hipping and fast T/A. US :3-5 days, UK: 4-7 days, Canada: 3-7 days, Europe: 6-10 days


If you need quality products and timely delivery then you do not need to go anywhere else,

just contact us and we serve you a lot better then anyone else

 

Our Advanteges


1. Sufficient stock. We can delivery promptly at the very day when receive the payment
2. Sophisticated and professional logistic agent. We take responsibility to provide our customers with fast delivery and secure shipping
3. Well-trained and disciplined packing team. Unique ways to ship 10 grams to 100kg powders at one time to your destination. Fast and discreet shipment could be arranged for customs pass Guaranteed.
4. Packing pictures and tacking code are provided within 12 hours after receiving the payment. Updated tracking information will be provided every other day.
5. After-sale service: Any questions or problems after receiving the product, please feel free to contact us. Problems would be solved immediately.


Ms. Daisy
skype Ms. Daisy

Tel: 86-27-88211875
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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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