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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Antibiotics raw powder Immunity inhibitor CAS 104987-11-3 Tacrolimus manufacturer


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Antibiotics raw powder Immunity inhibitor CAS 104987-11-3 Tacrolimus 

Price: 1.0 USD 
Payment Terms: T/T,WU,Money Gram 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: macrolides antibiotics
Production Capacity: 500kgs/month
Delivery Date: within 48hours after receiv...
CAS No.: 104987-11-3
Apperance: white powder
MOQ: 10g
Grade: Medical grade
Means of Transport: Ocean,Land,Air;Courier Expr...
Packing: discreet pkg
Brand Name: YCGC
Purity: 99%
Payment: T/T,West Union,Money Gram,e...
Usage: macrolides antibiotics
Price: change according to the mar...

Antibiotics raw powder Immunity inhibitor CAS 104987-11-3 Tacrolimus
Tacrolimus is used to prevent rejection of organ transplants.
Tacrolimus 99%.

Antibiotics raw powder Immunity inhibitor CAS 104987-11-3 Tacrolimus

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Tacrolimus (also FK-506 or fujimycin, trade names Prograft, Advagraf, Protopic) is an immunosuppressive drug used mainly after allogeneic organ transplant to lower the risk of organ rejection. It achieves this by inhibiting the production of interleukin-2, a molecule that promotes the development and proliferation of T cells, which are vital to the body's learned (or adaptive) immune response. Tacrolimus is also used in the treatment of other T cell-mediated diseases such as eczema (for which it is applied to the skin in a medicated ointment), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, Kimura's disease, and the skin condition vitiligo.

Chemically it is a 23-membered macrolide lactone that was first discovered in 1987 from the fermentation broth of a Japanese soil sample that contained the bacterium Streptomyces tsukubaensis.

Tacrolimus Spec.

Synonym: prograf; tsukubaenolide

CAS: 104987-11-3

MF: C44H69NO12

MW: 804.02

Purity: 99%

Melting Point: 113-115° C

Boiling Point: 871.7 ° C at 760 mmHg

Appearance: White powder

Storage: Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container.

Medical uses

It has similar immunosuppressive properties to ciclosporin, but is much more potent. Immunosuppression with tacrolimus was associated with a significantly lower rate of acute rejection compared with ciclosporin-based immunosuppression (30.7% vs 46.4%) in one study.Clinical outcome is better with tacrolimus than with ciclosporin during the first year of liver transplantation.Long-term outcome has not been improved to the same extent. Tacrolimus is normally prescribed as part of a post-transplant cocktail including steroids, mycophenolate, and IL-2 receptor inhibitors such as basiliximab. Dosages are titrated to target blood levels.

Usage :

Tacrolimus is used to prevent rejection of organ transplants. 

Tacrolimus is 10 to 100 times superior to cyclosporin in improving graft survival and preventing acute rejection after transplantation, but decreasing the toxin side effects.

Tacrolimus is an Anti-rejection in organ transplantation.

Tacrolimus is can treat skin diseases. like atopic dermatitis (AD), systemic lupus erythematosus (SLE), autoimmune ,eye disease and other autoimmune diseases.

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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]

Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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