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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Active Pharmaceutical Ingredients CAS 220127-57-1 Imatinib Mesylate manufacturer

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Active Pharmaceutical Ingredients CAS 220127-57-1 Imatinib Mesylate 

Price: 1.0 USD 
Payment Terms: T/T,WU,Money Gram;BItcoin 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: pharam raw powder
Production Capacity: 5000kg per month
Delivery Date: within 24 hours after payme...
CAS No.: 220127-57-1
Imatinib Mesylate color: white
Imatinib Mesylate Alias: Imatinib Mesylate, Gleevec,...
Imatinib Mesylate MOQ: 10grams
Imatinib Mesylate payment methods: T/T, Westeron Union, Money ...
Imatinib Mesylate Standard: USP
Means of Transport: Ocean,Air;express
Packing: disguised package
Brand Name: Imatinib Mesylate
Purity: 99%
Imatinib Mesylate appearence: powder
Imatinib Mesylate MF: C30H35N7O4S
Imatinib Mesylate Usage: Anti tumor drug
Imatinib Mesylate lead time: within 24hour after payment...
Imatinib Mesylate Delivery time: 5-7 days

Imatinib Mesylate is mainy used for anti tumor
Imatinib Mesylate is a tyrosine kinase inhibitor
Imatinib Mesylate raw powder in stock with low price

99% Purity Pharmaceutical Raw Material Imatinib Mesylate

Active Pharmaceutical Ingredients CAS 220127-57-1 Imatinib Mesylate


Imatinib Mesylate Basic information


Product Name:Imatinib Mesylate

CAS:220127-57-1

MF:C30H35N7O4S

MW:589.71

Assay:99%min

Appearence:White powder

Drug category:Anti tumor drug

Purpose:A tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL).

Package:1kg/bag


Imatinib Mesylate Product Description


Imatinib mesylate is a tyrosine kinase inhibitor IC50 value of 100 nM, 100 nM, 600 nM for v-Abl, c-kit, PDGFR, respectively.


Imatinib Mesylate is a specific tyrosine kinase (abl, c-kit, and PDGFR) inhibitor and is reported to sensitize cells to radio- or chemo-therapy. When tested with Y-79 and WERI-RB-1 Rb cell lines, imatinib mesylate treatment decreased the cell proliferation and invasion with the concentration of 10 μM . In osteoblast cells, administration of imatinib mesylate decreased osteoclast development via stimulating differentiation, inhibiting proliferation and survival .


In dog model with mast cell tumor, administration of imatinib mesylate at a dose of 10 mg/kg daily for 1-9 weeks reduced tumor growth via inhibiting tyrosine kinase .



Imatinib Mesylate Applications 


Cells were stimulated with allogeneic mature DCs or PHA in the presence of imatinib mesylate. The drug inhibited T-cell proliferation as a function of concentration. The effects were significant at 0.5 μM imatinib mesylate for the cells stimulated by DCs and at 1.0 μM imatinib mesylate for the cells stimulated with PHA. The IC50 values for imatinib mesylate-inhibited T-cell proliferation stimulated by DCs and PHA were 3.9 μM and 2.9 μM, respectively..


A tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL)


Imatinib Mesylate is orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively. Imatinib also known as Gleevec, Glivec, CGP-57148B, STI-571 & Imatinib


Imatinib Mesylate (STI571) is an orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively.


echinocandin antifungal, active against infections with Aspergillus and Candida, inhibits cell wall synthesis


Imatinib Mesylate Dosage


Starting dose: in patients with chronic myelogenous leukemia radically increasing stage and accelerating stage, imatinib mesylate in the recommended dose of 600 mg/day; Chronic-phase of interferon treatment failure, and cannot be removed surgically or metastatic malignant gastrointestinal stromal tumors (GIST) patients, and the recommended dose of 400 mg/day, both for once-daily oral, appropriate medication when eating, and drinking a glass of water, as long as effective, should be continued.


About US


We always willing to make a better deal for you. For regular customers we are giving great offers.

Oncce one become our customer, he will definitely return for another order.


Our mission is to provide our customer with an excellent personal service which develops long-term relationship, meeting their specific needs within budget and time frame. Ensure regulatory compliance are maximize on clients core competencies and product quality through optimized validated and controlled processes.


We have customer desired packing methods chosen and recommended by most of our customers.

We do pack as the customer desires the package to be packed....


All products are produced under GMP conditions according to Standard Operation Procedure(SOP), 

not from little underground labs or black markets, so the quality is guaranteed.


Prices depends on your order but we always encourage new clients to place sample / small orders and check our service, 

products and our communication and then gradually do your regular business with us. Of course bulk orders will enjoy discounts.


All products are bulk in stock, usually ship within 24-48 hours of your order being received and processed. Fast Express Delivery ,Available with UPS,FedEx,EMS,DHL,TNT and so on, 

secure hipping and fast T/A. US :3-5 days, UK: 4-7 days, Canada: 3-7 days, Europe: 6-10 days


If you need quality products and timely delivery then you do not need to go anywhere else,

just contact us and we serve you a lot better then anyone else

 

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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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