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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Pharma Raw Powder Antineoplastic Erlotinib hydrochloride / Erlotinib HCL CAS:183319-69-9 manufacturer

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Pharma Raw Powder Antineoplastic Erlotinib hydrochloride / Erlotinib HCL CAS:183319-69-9 

Price: 0.1 USD 
Payment Terms: T/T,WU,Money Gram 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: Anti-Cancer Powder
Production Capacity: 200kgs/month
Delivery Date: within 48hours after receiv...
CAS No.: 183319-69-9
Name: Erlotinib hydrochloride
Molecular Formula: C22H24ClN3O4
Usage: pharmaceutical material, St...
MOQ: 10g
Means of Transport: Ocean,Land,Air;Courier Expr...
Packing: dicreet pkg
Brand Name: YCGC
Purity: 99%
Apperance: white Powder
Molecular weight: 429.9
storage: Keep in cool and dry place,...
Payment: T/T,Western Union,Moneygram...

Pharma Raw Powder Antineoplastic Erlotinib hydrochloride / Erlotinib HCL CAS:183319-69-9
Erlotinib hydrochloride (trade name Tarceva) anti-cancer.


Pharma Raw Powder Antineoplastic Erlotinib hydrochloride / Erlotinib HCL CAS:183319-69-9


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Product Name :Erlotinib hydrochloride

CAS:183319-69-9

MF:C22H24ClN3O4

MW:429.9

Chemical Properties:Off-White Solid

Usage:

Selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor. Antineoplastic

Erlotinib HCl is an HER1/EGFR inhibitor with IC50 of 2 nM.

Erlotinib HCl (OSI-744) is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl. Phase 3.


Description:

Erlotinib hydrochloride (trade name Tarceva) is a d rug used to treat non-small cell lung cancer (NSCLC), pancreatic cancer and several other types of cancer. It is a receptor tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR).


Erlotinib Hydrochloride is a small molecule inhibitor of the EGFR/HER-1 (human epidermal growth factor receaptor) tyrosine kinase. Overexpression of the EGFR is present in many carcinomas, and inhibition of the activating kinase by Erlotinib provides a chemical intervention upon these systems. The inhibition of this tyrosine kinase effectively blocks EGFR activity but does not suppress tumor growth. When combined with 3,3'-diindolylmethane (sc-204624), efficacy against tumor proliferation was demonstrated.


Use in Cancer

Erlotinib hydrochloride is approved to be used alone or with other d rugs to treat:


1)Non-small cell lung cancer (NSCLC).It is used as first-line treatment for metastatic NSCLC in patients with tumors that have certain epidermal growth factor receptor (EGFR) mutations.It is used for locally advanced or metastatic NSCLC in patients who have already been treated with chemotherapy.


2)Pancreatic cancer. It is used with gemcitabine hydrochloride in patients whose disease cannot be removed by surgery or has metastasized.Erlotinib hydrochloride is also being studied in the treatment of other types of cancer.


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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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