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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Pharma Raw Powder Lamotrigine / Lamictal For Treatment Of Epilepsy And Bipolar Disorder CAS: 84057-84-1 manufacturer

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Pharma Raw Powder Lamotrigine / Lamictal For Treatment Of Epilepsy And Bipolar Disorder CAS: 84057-84-1 

Price: 1.0 USD 
Payment Terms: T/T,WU,Money Gram 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: anticonvulsant
Production Capacity: 500kgs/month
Delivery Date: within 48hours after receiv...
CAS No.: 84057-84-1
Apperance: off-white Powder
Qualitification: ISO 9001, KOSHER,UKAS
Grade: Medical grade
Delivery: Within 24hours after paymen...
Means of Transport: Ocean,Land,Air
Packing: safety and discreet pkg
Brand Name: YCGC
Purity: 99%
Payment: T/T,West Union,Money Gram,e...
Usage: anticonvulsant
Price: change according to the mar...

Pharma Raw Powder Lamotrigine / Lamictal For Treatment Of Epilepsy And Bipolar Disorder CAS: 84057-84-1
Lamotrigine
Lamictal
Lamotrigine
Lamicta

 


Pharma Raw Powder Lamotrigine / Lamictal For Treatment Of Epilepsy And Bipolar Disorder CAS: 84057-84-1


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Product Name: Lamotrigine

Synonyms:4-Triazine-3,5-Diamine,6-(2,3-Dichlorophenyl)-2;3,5-Diamino-6-(2,3-Dichlorophenyl)-1,2,4-Triazine;6-(2,3-Dichlorophenyl)-1,2,4-Triazine-3,5-Diamine;Lamictal;Lamotrigin

CAS: 84057-84-1

MF:C9H7Cl2N5

MW:256.09

EINECS:281-901-8

Lamotrigine Chemical properties:

Chemical Properties:White to Cream Coloured Powder

Melting point:177-181ºC

Solubility:DMSO: 20 mg/mL at 60 °C, soluble


Lamotrigine Description

Lamotrigine, originally marketed as Lamictal and available under many brands worldwide, is an anticonvulsant d rug used in the treatment of epilepsy and bipolar disorder. It is also used off-label as an adjunct in treating clinical depression.


For epilepsy, it is used to treat focal seizures, primary and secondary tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. Like many other anticonvulsant medications, lamotrigine also seems to act as an effective mood stabilizer, and has been the first US Food and D rug Administration (FDA)-approved d rug for this purpose since lithium, a d rug approved almost 30 years earlier. It is approved for the maintenance treatment of bipolar type II.


Lamotrigine is a synthetic phenyltriazine with anti-epileptic and analgesic properties. Lamotrigine enhances the action of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which may result in a reduction of pain-related transmission of signals along nerve fibers. This agent may also inhibit voltage-gated sodium channels, suppress glutamate release, and inhibit serotonin reuptake.


Lamotrigine Usage:

For the adjunctive treatment of partial seizures in epilepsy and generalized seizures of Lennox-Gastaut syndrome. Also for the maintenance treatment of bipolar I disorder and depression.

Biological Activity:Anticonvulsant. Inhibits glutamate release, possibly through inhibition of Na + , K + and Ca 2+ currents.


Lamotrigine Medical uses


Epilepsy

Lamotrigine is approved in the US for the treatment of partial seizures.[8] It is considered a first-line d rug for primary generalised tonic-clonic seizures (includes simple partial, complex partial and secondarily generalised seizures), and as an adjuvant therapy in partial seizures (focal onset tonic-clonic, atypical absence, myoclonic, and due to Lennox-Gastaut syndrome). As well, it is used as an alternative d rug for absence seizure and atypical absence, myoclonic, and atonic seizures.[9][10]

Lamotrigine is one of a small number of FDA-approved therapies for seizures associated with Lennox-Gastaut syndrome, a severe form of epilepsy. Typically developing before four years of age, LGS is associated with developmental delays. There is no cure, treatment is often complicated, and complete recovery is rare. Symptoms include the atonic seizure (also known as a "drop attack"), during which brief loss of muscle tone and consciousness cause abrupt falls. Lamotrigine significantly reduces the frequency of LGS seizures, and is one of two medications known to decrease the severity of drop attacks.[11] Combination with valproate is common, but this increases the risk of lamotrigine-induced rash, and necessitates reduced dosing due to the interaction of these d rugs.

 

Bipolar disorder

Lamotrigine is approved in the US for maintenance treatment of bipolar I disorder.[13] While traditional anticonvulsant d rugs are predominantly antimanics, lamotrigine is most effective for preventing the recurrent depressive episodes of bipolar disorder. The d rug seems ineffective in the maintenance of current rapid-cycling, acute mania, or acute depression in bipolar disorder; however, it is effective at prevention of or delaying the mania, depressive, or rapid cycle.[14] According to studies in 2007, lamotrigine may treat bipolar depression without triggering mania, hypomania, mixed states, or rapid-cycling.


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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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