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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China CAS 25316-40-9 Doxorubicin Hydrochloride/Doxorubicin HCl China Best Supplier manufacturer

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CAS 25316-40-9 Doxorubicin Hydrochloride/Doxorubicin HCl China Best Supplier 

Price: 90.0 USD 
Payment Terms: T/T,D/A,WU,Money Gram;Bitcoin 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Means of Transport: Ocean,Air;Express
Packing: disguise package or as requ...
Brand Name: gongchuang
Purity: 99%
source: Doxorubicin HCl
supplier: Doxorubicin HCl
Usage: for medical
purity: 99% min
Standard: USP/BP/USP
Production Capacity: 500kg//month
Delivery Date: 4-15days
CAS No.: 25316-40-9
Alias: Doxorubicin HCl
usage: Doxorubicin HCl
price: Doxorubicin HCl
effects: medcine raw
Appearance: powder

Doxorubicin Hydrochloride/Doxorubicin HCl ;
CAS 25316-40-9 Doxorubicin Hydrochloride/Doxorubicin HCl China Best Supplier

Top Quality 99% CAS 25316-40-9 Doxorubicin hydrochloride/Doxorubicin Hcl

 

Doxorubicin Hcl Product Name:Doxorubicin hydrochloride
Doxorubicin Hcl Alias:Adriamycin,
Doxorubicin Hcl CAS NO.:25316-40-9
Doxorubicin Hcl EINECS:246-818-3
Doxorubicin Hcl Molecular Formula:C27H29NO11.HCl
Doxorubicin Hcl Molecular Weight:579.99
Doxorubicin Hcl Appearance:Orange powder

 

Doxorubicin,also known as hydroxydaunorubicin and hydroxydaunomycin, is a drug used in cancer chemotherapy and derived by chemical semisynthesis from a bacterial species.It is an anthracycline antitumor antibiotic (note: in this context, this does not mean it is used to treat bacterial infections) closely related to the natural product daunomycin and like all anthracyclines, it works by intercalating DNA, with the most serious adverse effect being life-threatening heart damage.

 

It is commonly used in the treatment of a wide range of cancers, including hematological malignancies (blood cancers, like leukaemia and lymphoma), many types of carcinoma (solid tumours) and soft tissue sarcomas.It is often used in combination chemotherapy as a component of various chemotherapy regimens.


Doxorubicin Hydrochloride Basic Info.

Synonyms:Doxorubici hydrochloride, Adriacin, Doxorubici, Adriamycin;
Assay:99%
CAS No.:25316-40-9
MF:C27H30CLNO11
MW:579.98
Appearance:Orange-red or red crystalline powder;
Storage:Keep in a dry, cool and ventilated place
Category:Raw anabolic material for the treatment of cancer

Doxorubici Hydrochloride Description:
It is a drug used in cancer chemotherapy. It is an anthracycline antibiotic, closely related to the natural product daunomycin, and like all anthracyclines, it works by intercalating DNA, with the most serious adverse effect being life-threatening heart damage. It is commonly used in the treatment of a wide range of cancers, including hematological malignancies, many types of carcinoma, and soft tissue sarcomas.

Doxorubici Hydrochloride Applications:
1 Hodgkin's disease and lymphosarcoma, reticulum cell sarcoma. 
2 undifferentiated small cell and non-small cell lung cancer, breast cancer. 
3 acute lymphoblastic and myeloid leukemia. 
4 osteosarcoma and soft tissue sarcoma. 
5 ovarian cancer, testicular cancer, bladder cancer, . Wilms cancer, prostate cancer, thyroid cancer, neuroblastoma cancer, esophageal cancer, stomach cancer, liver cancer, cervical cancer and head and neck cancer. Multiple myeloma, pancreatic cancer, endometrial cancer and brain tumors can also be applied. 


Doxorubicin hydrochloride COA:

Product NameDoxorubicin hydrochloride(C27H30ClNO11)CAS:25316-40-9
Items TestedSpecificationResult
Purity98.0~102.0%99.02%
DescriptionOrange-red or red crystalline powder; No visible
evidence of contamination by foreign matter.
Confirm
Identification AIR spectrum corresponds to the IR spectrum of the reference standardConfirm
Identification BThe retention time of the doxorubicin peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.Confirm
SolubilitySoluble in water and methanol; slightly soluble in ethanol; practically insoluble in acetone.Conforms
Residual Solvents

Acetone≤ 0.5%0.31%
Acetone +Ethanol≤ 2.5%0.60%
methanol≤ 0.3%Not detected
Dichloromethane≤ 0.06%Not detected
pH4.0 to 5.55.1
Water Content≤ 4.0%0.8%
Related Substances

Impurity A (Doxorubicinone)≤ 0.5%0.1%
Any Other unknown Impurity≤ 0.1%0.07%
Total unknown Impurities≤ 0.3%0.2%
Total Impurities≤ 1.0%0.9%
ConclusionIt complies to reference standard





Uses: This product is suitable for breast cancer, lung cancer, soft tissue tumors, osteosarcoma, bladder cancer, testicular cancer, thyroid cancer, neuroblastoma cancer, Wilms cancer, malignant lymphoma and acute leukemia, can also be used for liver cancer, stomach cancer, ovarian cancer, cervical cancer, head and neck cancer, multiple myeloma, pancreatic cancer, esophageal and endometrial tumors.

Description;

Doxorubicin Hydrochloride is the hydrochloride salt of doxorubicin, an anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from the bacterium Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin. Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis. Additionally, doxorubicin inhibits topoisomerase II which results in an increased and stabilized cleavable enzyme-DNA linked complex during DNA replication and subsequently prevents the ligation of the nucleotide strand after double-strand breakage. Doxorubicin also forms oxygen free radicals resulting in cytotoxicity secondary to lipid peroxidation of cell membrane lipids; the formation of oxygen free radicals also contributes to the toxicity of the anthracycline antibiotics, namely the cardiac and cutaneous vascular effects.

Doxorubicin hydrochloride is also being studied in the treatment of other types of cancer.
Doxorubicin hydrochloride is also available in a different form called doxorubicin hydrochloride liposome.

Specifications:
 

English name:DOXORUBICIN HCL
Alias:DOXORUBICIN HCL
CAS25316-40-9
Molecular formulaC27H30ClNO11
Molecular weight 579.98
Content99%
Appearanceorange-red loose-like lumps or powder
Pricenegotiate
MOQ20g
paymentT/T , West Union , Money Gram
Packing:According to customer requirements for packaging
Shipping wayDHL, TNT, FEDEX, HKEMS, UPS
Shipping feeWithin 500g is $45
Delivery timeWithin 24 hours after you pay and should arrive your hands within 7 days
After-sales serviceGive you the tracking number ASAP after your products send out
 
Also will give you the way to help you convert the powder into injection


Our advantage:
 

PackageDo not need to worry about the customs problem,we will use discreet package,very safe.
Fast Deliveryabout 4-7days by TNT, FedEx, EMS, DHL(Door-to-Door).
Quality  GMP lab to guarantee the quality with good price
Sample Sample available at any time
ResendIf your parcel is lost or detained, please inform me immediately, We will re-send your parcel, this is our policy
Payment TermsWestern Union/ Money Gram/ Bank Transfer/ Bitcoin/ Paypal for your option.


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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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