Post Offer Free
Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Long Acting Anesthetic Drug Raw Powder Prilocaine CAS 1786-81-8 manufacturer

2nd

Gold Index: 167643

You are here: home  > Pharmaceutical raw material  > Other pharmaceuticals  > Long Acting Anesthetic Drug Raw Powder Prilocaine CAS 1786-81-8

Long Acting Anesthetic Drug Raw Powder Prilocaine CAS 1786-81-8 

Price: 90.0 USD 
Payment Terms: T/T,D/A,WU,Money Gram;Bitcoin 
Place of Origin: Hubei, China (Mainland) 
inquire skype
Add to My Favorites
HiSupplier Escrow
Share |

Product Detail

Means of Transport: Ocean,Air;Express
Packing: disguise package or as requ...
Brand Name: gongchuang
Purity: 99%
source: Tetracaine
supplier: Tetracaine
Usage: for medical
purity: 99% min
Standard: USP/BP/USP
Production Capacity: 500kg//month
Delivery Date: 4-15days
CAS No.: 1786-81-8
Alias: Tetracaine
usage: Tetracaine
price: Tetracaine
effects: medcine raw
Appearance: powder

Pain Killer Tetracaine HCl Lidocaine Benzocaine Procaine Tetracaine
Potent Local Anesthetic Pharmaceutical Tetracaine Hydrochloride / Tetracaine

Long Acting Anesthetic Drug Raw Powder Prilocaine Base CAS 721-50-6

Product Name: Prilocaine
Synonyms: Prilocaine base
Prilocaine CAS: 721-50-6
Prilocaine MF: C13H20N2O
Prilocaine MW: 220.31
Prilocaine EINECS: 211-957-0
Prilocaine Appearance: Almost white powder
Quality standard: USP37
Purity: 99.67%
Melting point: 36~39°C
Solubility: Very soluble in alcohol and in acetone; slightly soluble in water.
Shelf life: 2 years
Prilocaine Product Categories: Active Pharmaceutical Ingredients; Inhibitors
Prilocaine Usage: It is a kind of local anesthetic drug. The product has better efficacy than procaine and the local anesthesia intensity and speed being similar as lidocaine but with longer duration time and less toxicity as well as smaller accumulation effect. It is suitable for epidural anesthesia, conduction anesthesia and infiltration anesthesia.




2, Prilocaine Applications:

Prilocaine is a local anesthetic of the amino amide type. In its injectable form, it is often used in dentistry. It is also often combined with lidocaine as a topical preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA).

Prilocaine topical is a local anesthetic (numbing medication). It works by blocking nerve signals in your body.
Prilocaine topical is used to numb the skin, or surfaces of the penis or vagina, in preparation for a medical procedure or to lessen the pain of inserting a medical instrument such as a tube or speculum.
Prilocaine belongs to amide local anesthetic drug with its anesthesia intensity and speed being similar as lidocaine but with a longer duration period and weaker effect on vasodilation. It has a lower toxicity than lidocaine. It is clinically for local anesthesia, especially suitable for treating patients who are not allowed to use adrenaline.

[Pharmacological] its 3% solution has a similar local anesthesia efficacy as the anesthesia drug of 2% lidocaine together with . It has a slow onset time which lasts about 6~7min and the duration time of about 1.5~2h. It has a strong penetration capability through mucous membranes. has a slightly prolonged duration of action. PPB is 55% and T1/2 of about 1.5h. It is subject to liver metabolism with its metabolites nitroso toluidine being able to oxidize hemoglobin to form methemoglobin. It can be transported to the fetus through the placenta.

[Adverse reactions] once the usage amount exceeds 600mg, methaemoglobinaemia can occur with cyanosis, tachycardia, headache, dizziness and weakness occurring.
[Note] patients of anemia, congenital or acquired methaemoglobinaemia, respiratory failure or heart failure and hypoxic patients should be disabled. It is forbidden for applied to obstetric anesthesia.



[Usage and dosage]

Infiltration anesthesia: 0.5% to 1% solution with the duration of action of 1 to 1.5 hours.
Nerve blocking anesthesia: use 1% to 2% solution with the duration of action being 2-3 hours.
Epidural anesthesia: use10 to 30 mL of 1.5%~1% solution with the duration of action of 2.5 to 3.5 hours. Use a maximum dose of 600 mg.


COA

TestsResultsSpecifications
DescriptionAlmost white powderWhite or almost white powder
SolubilityCompliesVery soluble in alcohol and in acetone; slightly soluble in water.
IdentificationCompliesBy IR, to match with the working standard
Melting point37.5~38.9°C36~39°C
Water0.03%≤0.5%
Residue on ignition0.05%≤0.1%
Related compound ANot detected≤0.01%
Related compoundsCompliesnot more than 0.2% of any individual impurity
Compliesnot more than one impurity exceeds 0.1%
0.13%not more than 0.5% of total impurities
Residual solventsNot detectedDichloromethane Not more than0.06%
Not detectedEthanol Not more than0.5%
0.04%Isopropyl ether Not more than0.5%
Assay99.67%≥99.0% (on the anhydrous basis)
Conclusion: Conforms to USP37 standard.

Surface Anesthesia Powder:
Benzocaine (CAS:94-09-7)
Tetracaine Hydrochloride (CAS:136-47-0)
Tetracaine (CAS.94-24-6)
 
Procaine Hydrochloride (CAS:51-05-8)
Lidocaine Hydrochloride (CAS:73-78-9)
Baclofen (CAS:1134-47-0)
Prilocaine(CAS.721-50-6)
 
Flurbiprofen(CAS.5104-49-4)
Fluticasone Propionate(80474-14-2)
Pentoxifylline(CAS.6493-05-6)
Gabapentin Hydrochloride(CAS.60142-96-3)
Ropivacaine Mesylate(CAS.854056-07-8)
 
Lidocaine(CAS.137-58-6)
Procaine(CAS.59-46-1)
 
Articaine Hydrochloride(CAS.23964-57-0)
 
Benzocaine Hydrochloride(CAS.23239-88-5)
 
Propitocaine Hydrochloride(CAS.1786-81-8)
Proparacaine Hydrochloride(CAS.5875-06-9)
 
Ropivacaine Hydrochloride(CAS.132112-35-7)
 
Pramoxine Hydrochloride(CAS.637-58-1)
 
Dibucaine Hydrochloride(CAS.61-12-1)
Levobupivacaine Hydrochloride(CAS.27262-48-2)
Product namePrilocaine/Propitocaine HydrochlorideMFG. Date2016-08-30
Package1kg/bagBatch numberFH2016-08-30
Testing Date2016-08-30Exp Date2018-08-30
StandardUSP36Quantity800kg
Cas No.1786-81-8EINECS217-244-0
Molecular FormulaCl3H20N2O·HClMolecular Weight256.7716
FunctionMain functions are as follows:
1. Local anesthetic.
ApplicationsMain applications are as follows:
The material for Local anesthetic.
Items TestedSpecificationResult
CharactersWhite or almost white crystalline powderConfirms
Melting Point166ºC-169ºC166.5ºC-168.5ºC
SolubilityFreely soluble in water and in alcoholConfirms
Assay (HPLC)99.0--101.0% (calculated on the dried basis)99.6%
Loss on DryingNot more than 0.3%0.16%
Related substancesNot more than 1.0%0.11%
AcetoneNot more than 5000ppmconforms
EthanolNot more than 5000ppmconforms
Sulphated ashNot more than 0.15%conforms
Heavy MetalNot more than 0.001%<0.001%
ConclusionConforms USP36


Ms. Gina
skype Ms. Gina
Manager
Tel: 86-27-88211875
Mobile: 188 7222 0799
Contact to this supplier

Didn't find what you're looking for? Post Buying Lead or contact HiSupplier Customer Service Center  for help!

Related Search

Find more related products in following catalogs on Hisupplier.com

Other products from this supplier

Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

Follow Us: Follow us on facebook Follow us on linkedin Follow us on Twitter

Gina:   skype
Service:   skype

You May Like: