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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Pharma Grade Raw Powder Bicalutamid Treat Prostate Cancer CAS NO: 90357-06-5 manufacturer

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Pharma Grade Raw Powder Bicalutamid Treat Prostate Cancer CAS NO: 90357-06-5 

Price: 1.0 USD 
Payment Terms: T/T,WU,Money Gram 
Place of Origin: Hubei, China (Mainland) 
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Model No.: pharma raws powder
Production Capacity: 5000kgs/month
Delivery Date: within 48hours after receiv...
CAS No.: 90357-06-5
Payment: T/T,Western Union,Moneygram...
Usage: bodybuilding
Price: change according to the mar...
Delivery: Within 24hours after paymen...
Means of Transport: Ocean,Land,Air;Courier Expr...
Packing: discreet pkg
Brand Name: YCGC
Purity: 99%
Apperance: liquid
User: Adult
MOQ: 10g

Pharma Grade Raw Powder Bicalutamid Treat Prostate Cancer CAS NO: 90357-06-5
Pharma Grade Raw Powder Bicalutamid Treat Prostate Cancer CAS NO: 90357-

Pharma Grade Raw Powder Bicalutamid Treat Prostate Cancer CAS NO: 90357-06-5


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Name:Bicalutamid

Other name: N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hydroxy-2-methyl-propanamide

Application:With luteinising-hormone-releasing hormone (LHRH) analogues or surgical orchiectomy combined applied in the treatment of advanced prostate cancer. 

CAS NO: 90357-06-5

Structural formula: C18H14F4N2O4S

Molecular weight: 430.37

Appearance: white powder

Use:Objective To evaluate the efficacy of bicalutamid ( casodex) in the treatment of hormone-refractory prostate cancer


Product Description:


Bicalutamid has a molecular weight of 430.37. The pKa' is approximately 12. Bicalutamid is a fine white to off white powder which is practically insoluble in water at 37°C (5 mg per 1000 mL), slightly soluble in chloroform and absolute ethanol, sparingly soluble in methanol, and soluble in acetone and tetrahydrofurans.CASODEX (bicalutamid) is a racemate with its antiandrogenic activity being almost exclusively exhibited by the R-enantiomer of bicalutamid; the S-enantiomer is essentially inactive.


Applications:


Bicalutamid is used primarily in the treatment of early and advanced prostate cancer. It is approved at a dosage of 50 mg/day as a combination therapy with a gonadotropin-releasing hormone (GnRH) analogue or orchiectomy (that is, surgical or medical castration) in the treatment of stage D2 metastatic prostate cancer (mPC), and as a monotherapy at a dosage of 150 mg/day for the treatment of stage C or D1 locally advanced prostate cancer (LAPC). Although effective in mPC and LAPC, bicalutamid is no longer indicated for the treatment of localized prostate cancer (LPC) due to negative findings in the Early Prostate Cancer (EPC) trial.


Uses:


Bicalutamid is used to treat prostate cancer that has spread to other areas of the body. It is used in combination with hormone treatment. This medication works by blocking the action of male hormones in the prostate, slowing growth of the tumors.

How to use bicalutamid

Read the Patient Information Leaflet if available from your pharmacist before you start taking bicalutamid and each time you get a refill. If you have any questions, ask your doctor or pharmacist.


Dosage and administration:


Adult: adult males including the elderly: one (50mg), once a day. The treatment should be started simultaneously with LHRH analogue therapy or surgical orchiectomy.

Children: This product is contraindicated in children.


Renal impairment: The patients with renal impairment don't need dose adjustment.

Hepatic impairment: The patients with mild liver damage don't need dose adjustment, while the patients with severe liver damage may occur d rug accumulation (see precautions).



Precautions:


This product is widely metabolized in the liver. Data show that patients with severe liver damage may slow down d rug clearance, which may lead to accumulation. So the patients with moderate and severe liver injury should use it with caution.


The patients may appear liver changes by using it, so it should be considered regular liver function tests. The main changes generally appear within the first 6 months of treatment using this product.


Severe changes in liver function are rarely visible in the treatment of the product (see Adverse Reactions). If there is a serious change in treatment using this product, it should be discontinued.


This product is shown to inhibit the activity of cytochrome P450 (CYP3A4). When combined with d rugs metabolised mainly by CYP3A4, the patients should be caution (see Contraindications and D rug Interactions).


Pregnancy and lactation: This product is contraindicated in women, especially for pregnant women or nursing mothers.


Effect on driving and operating machinery ability: This product does not affect the ability of patients of driving and operating the machine. 

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ABOUT US

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We're specialized in pharma.raw materials ( hormone steroid powders, Steroids injectable liquids,peptides,Sarms), our company integrates R&D, producing, operating and marketing into an organic whole. We have authority of export and import, and have experience of export for 15 years. 


Major Market: United States, United Kingdom, Australia, Canada, Sweden, Russia, Poland, Brazil, Israel, Netherlands, Germany,Spain, Switzerland, Poland and so on.


MOQ:10g


Package:Disguised & Discreet pkg

Payment:T/T,Western Union,Moneygram,bitcoin

Delivery: sent out the goods within 24hours after receiving payment.

Custom Pass rate:99%

Resend policy is available if the parcle is seized or any quality problems been found.



After-sale Service :

Discounts are available for our second-time customers. We can provide recipes and professional suggestions to promote yourselves. Tracking number and packing photos can be given quickly after your goods sent. We are always here waiting for you!


Our main products in stock: 

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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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