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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Nootropic Powder Rivastigmine Tartrate For Treating Alzheimer's Disease CAS: 129101-54-8 manufacturer

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Nootropic Powder Rivastigmine Tartrate For Treating Alzheimer's Disease CAS: 129101-54-8 

Price: 1.0 USD 
Payment Terms: T/T,WU,Money Gram 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: nootropics raws
Production Capacity: 5000kgs/month
Delivery Date: within 48hours after receiv...
CAS No.: 129101-54-8
Payment: T/T,Western Union,Moneygram...
Usage: bodybuilding
Price: change according to the mar...
Delivery: Within 24hours after paymen...
Means of Transport: Ocean,Land,Air
Packing: discreet pkg
Brand Name: YCGC
Purity: 99%
Apperance: powder
User: Adult
MOQ: 10g
Category: Pharma Raws Powder

Nootropic Powder Rivastigmine Tartrate For Treating Alzheimer's Disease CAS: 129101-54-8
Nootropic Powder Rivastigmine Tartrate For Treating Alzheime

Nootropic Powder Rivastigmine Tartrate For Treating Alzheimer's Disease CAS: 129101-54-8


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Rivastigmine Tartrate Spec.

Synonyms:Rivastigmine Tartrate Salt; Sdz-Ena 713;Sdz-Ena 713;Ethylmethyl-Carbamic Acid 3-[(1s)-1-(Dimethylamino)Ethyl]Phenyl Ester, Bitartrate;Rivastigiminetartrate(Forr&Donly);(s)-n-Ethyl-3-[(1-Dimethylamino)Ethyl]-n-Methylphenylcarbamate Hydrogen Tartrate;Rivastigmine-d6 Tartarate

CAS: 129101-54-8

MF:C18H28N2O8

MW:400.42

Melting point:123-125ºC

Chemical Properties:White to Off-White Powder

Usage:A brain selective acetylcholinesterase inhibitor. Nootropic. Rivastigmine Tartrate, a cholinesterase inhibitor with IC50 of 5.5 μM, ues as a parasympathomimetic or cholinergic agent for the treatment of mild to moderate Alzheimer disease.


Interactions:

(1) Rivastigmine is mainly through hydrolysis cholinesterase metabolism, cytochrome P450 isozymes are rarely involved in its metabolism. Therefore, the product and by other d rugs metabolized by these enzymes does not exist pharmacokinetic interactions.

(2) study in healthy volunteers found the product (a single dose of 3mg) with digoxin, warfarin, dia zepam or fluoxetine, have no pharmacokinetic interactions. Warfarin induced by prothrombin time extension are not affected by this product. After combination of digoxin and the product found no adverse impact on cardiac conduction.

(3) In clinical studies of patients with Alzheimer's disease (AD), the goods and some commonly used prescription d rugs combined, such as antacids, antiemetics, hypoglycemic agents, β-blockers, calcium channel blockers agents, inotropic agents, anti-angina d rugs, non-steroidal anti-inflammatory d rugs, estrogens, analgesics, tranquilizers, antihistamines, etc., and risk of clinically relevant adverse reaction does not increase

(4) In view of the pharmacokinetic effect of this product, this product should not be used in combination with other cholinergic d rugs, it may interfere with the activity of anticholinergic d rugs.

(5) There is no experience of this product with anti Parkinson d rugs, anti anxiety d rugs (except for stability), antipsychotic d rugs, antiepileptic d rugs, antidepressant d rugs.

(6) rivastigmine tartrate as a cholinesterase inhibitor, during anesthesia, it can be used to enhance succinylcholine-type muscle relaxant effect.


Rivastigmine Tartrate Application:


For the treatment of mild to moderate Alzheimer's disease symptoms of dementia.


Pathological changes in Alzheimer's disease mainly involve the cholinergic nerve pathways from the basal forebrain to the cerebral cortex and hippocampus. These pathways are known to be related to attention, learning ability, memory, and other cognitive processes.


Carbamate tartrate is a carbamate-selective acetylcholinesterase inhibitor that promotes cholinergic nerve conduction by delaying the function of complete cholinergic neurons to release the release of acetylcholine. The results of animal experiments showed that valacridine tartrate could selectively enhance the effect of acetylcholine in cerebral cortex and hippocampus.


Therefore, Aisi can improve Alzheimer's disease in patients with cholinergic-mediated cognitive dysfunction. In addition, cholinesterase inhibitors can slow the formation of amyloid b-amyloid precursor protein (APP) fragments. Amyloid plaque is Alzheimer's disease tartaric acid rivastigmine by the target enzyme into a covalent complex and the latter temporarily lost activity.


The activity of acetylcholinesterase in cerebrospinal fluid (CSF) decreased by nearly 40% within 1.5 hours after 3 mg of human administration. After the d rug reaches its maximum inhibitory effect, the enzyme activity is restored to the basal level for approximately 9 hours. The inhibition of acetylcholinesterase in ruthenate tartrate in patients with Alzheimer's disease was dose-dependent, with a maximum test dose of 6 mg twice daily.

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MOQ:10g

Package:Disguised & Discreet pkg

Payment:T/T,Western Union,Moneygram,bitcoin

Delivery: sent out the goods within 24hours after receiving payment.

Custom Pass rate:99%

Resend policy is available if the parcle is seized or any quality problems been found.


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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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