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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Nootropic Raw Powder PRL-8-53 HCL Improve Memory CAS 51352-87-5 manufacturer

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Nootropic Raw Powder PRL-8-53 HCL Improve Memory CAS 51352-87-5 

Price: 1.0 USD 
Payment Terms: T/T,WU,Money Gram 
Place of Origin: Hubei, China (Mainland) 
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Model No.: nootropic raws powder
Production Capacity: 5000kgs/month
Delivery Date: within 48hours after receiv...
CAS No.: 51352-87-5
Payment: T/T,Western Union,Moneygram...
Usage: bodybuilding
Price: change according to the mar...
Delivery: Within 24hours after paymen...
Means of Transport: Ocean,Land,Air
Packing: discreet pkg
Brand Name: YCGC
Purity: 99%
Apperance: powder
User: Adult
MOQ: 10g
Category: Pharma Raws Powder

Nootropic Raw Powder PRL-8-53 HCL Improve Memory CAS 51352-87-5
Nootropic Raw Powder PRL-8-53 HCL Improve Memory CAS 51352-87-5
Nootropic Raw Powder

Nootropic Raw Powder PRL-8-53 HCL Improve Memory CAS 51352-87-5


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Name:PRL-8-53

Chemical name:Methyl 3-(2-(benzyl(methyl)amino)ethyl)benzoate

Synonyms:PRL-8053;PRL-8-53;Methyl 3-(2-(benzyl(Methyl)aMino)ethyl)benzoate hydrochloride;3-(2-Benzyl(methyl)aminoethyl)benzoic acid methyl ester hydrochloride;m-[2-(Benzylmethylamino)ethyl]benzoic acid methyl ester hydrochloride;Benzoic acid, 3-(2-(Methyl(phenylMethyl)aMino)ethyl)-, Methyl ester, hydrochloride

CAS 51352-87-5

MF:C18H22ClNO2

MW 319.82578

Dosage:

Subjects in human trials have been given up to 100 mg a day and did not appear to develop any negative side effects


Abstract

The effect of 3-(2-benzylmethylaminoethyl) benzoic acid methyl ester hydrochloride (PRL-8-53) on learning and on retention of verbal information in human subjects was investigated. Using the serial anticipation method under double-blind conditions it was found that PRL-8-53 causes slight improvement of acquisition. Retinetion of verbal information was found improved to a statistically significant degree (most P values better than 0.01, some better than 0.001). No significant changes were found for either visual reaction time or motor control after d rug when compared with placebo values.


Description

PRL-8-53 (chemical name Methyl 3-(2-(benzyl(methyl)amino)ethyl)benzoate) is a synthetic nootropic compound discovered in 1972 and patented in 1975 by the late Dr. Nikolaus Hansl, a neuropharmacologist at Creighton University in Omaha, Nebraska. Preliminary animal tests indicated that the compound was both safe and significantly nootropic, boosting avoidance learning in rodents with no adverse effects. But the real interest in PRL-8-53 was sparked by a 1978 study on human volunteers, which showed that a single dose of the compound could improve word retention scores by more than 200%.


HOW IT WORKS

PRL-8-53's exact mechanisms of action are not well understood, but it is generally believed to regulate the brain's production of and response to several crucial neurotransmitters. In his reports on human and animal studies Hansl indicated that PRL-8-53 potentiates dopamine, partially restricts production of serotonin, and enhances the brain's response to acetylcholine.


Though Hansl's research report on the 1978 human study suggests those actions, it does not clearly delineate the mechanism of action.The fact that older subjects saw the most nootropic benefit from taking the d rug supports the concept that dopamine modulation plays a major role in PLR-8-53's effects. Up-regulating the normal age-related lessening of dopamine production that is associated with cognitive decline could have a significant positive impact on both learning and memory.


Dosage 

The only human study on PRL-8-53 was based on the ingestion of a single 5 mg dose. There is no data on the effectiveness or potential toxicity of any other dosage in humans.


SIDE EFFECTS

No adverse effects from a single 5 mg dose of PRL-8-53 were observed in the human study. Animal studies suggest that the compound has a high therapeutic threshold, but evidence is very limited because no comprehensive toxicity studies have been completed.


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ABOUT US

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We're specialized in pharma raw materials ( hormone steroid powders, Steroids injectable liquids,peptides,Sarms), our company integrates R&D, producing, operating and marketing into an organic whole. We have authority of export and import, and have experience of export for 15 years. 


Major Market: United States, United Kingdom, Australia, Canada, Sweden, Russia, Poland, Brazil, Israel, Netherlands, Germany,Spain, Switzerland, Poland and so on.


MOQ:10g

Package:Disguised & Discreet pkg

Payment:T/T,Western Union,Moneygram,bitcoin

Delivery: sent out the goods within 24hours after receiving payment.

Custom Pass rate:99%

Resend policy is available if the parcle is seized or any quality problems been found.


After-sale Service :

Discounts are available for our second-time customers. We can provide recipes and professional suggestions to promote yourselves. Tracking number and packing photos can be given quickly after your goods sent. We are always here waiting for you!


Our main products are wait for you: 

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Solvents for Steroids: BA, BB, GSO, Guaiacol, EO, PEG etc.

Tools & Devices: Filter,Crimper,Vials, caps, ect. 


Any interested pls let me know.thanks.


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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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