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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Nootropic Sleep Aid Powder Suvorexant /MK-4305 Promote Sleep CAS:1030377-33-3 manufacturer

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Nootropic Sleep Aid Powder Suvorexant /MK-4305 Promote Sleep CAS:1030377-33-3 

Price: 1.0 USD 
Payment Terms: T/T,WU,Money Gram 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: nootropic raws powder
Production Capacity: 5000kgs/month
Delivery Date: within 48hours after receiv...
CAS No.: 1030377-33-3
Payment: T/T,Western Union,Moneygram...
Usage: bodybuilding
Price: change according to the mar...
Delivery: Within 24hours after paymen...
Means of Transport: Ocean,Land,Air
Packing: discreet pkg
Brand Name: YCGC
Purity: 99%
Apperance: powder
User: Adult
MOQ: 10g
Category: Pharma Raws Powder

Nootropic Sleep Aid Powder Suvorexant /MK-4305 Promote Sleep CAS:1030377-33-3
Nootropic Sleep Aid Powder Suvorexant /MK-4305 Promote Sleep 325Mesh.

Nootropic Sleep Aid Powder Suvorexant /MK-4305 Promote Sleep CAS:1030377-33-3


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Suvorexant (MK-4305) Spec.

Synonyms:5-Chloro-2-[(5R)-5-methyl-4-[5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl]-1,3-benzoxazole;MK 4305;(R)-(4-(5-chlorobenzo[d]oxazol-2-yl)-7-Methyl-1,4-diazepan-1-yl)(5-Methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)Methanone;Suvorexant;MK-4305 (Suvorexant);, [(7R)-4-(5-chloro-2-benzoxazolyl)hexahydro-7-Methyl-1H-1,4-diazepin-1-yl][5-Methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]-;Suvorexant (MK-4305);Suvorexant (with 4 ints.)

CAS:1030377-33-3

MF:C23H3ClN6O2

MW:450.92072

Melting point:153ºC

density:1.41

Product Categories: API;Inhibitors


Description:

MK-4305 is a novel sedative hypnotic d rug that is prescribed to promote sleep in patients with insomnia. It is a CNS depressant and blocks the binding of wake-promoting neuropeptides orexin A and orexin B to the two orexin receptors, thus, altering the signaling of orexin in the brain and suppressing the sleep-wake drive.


Suvorexant is a central nervous system (CNS) depressant and can impair daytime wakefulness even when used as prescribed. Prescribers should monitor for somnolence and CNS depressant effects, but impairment can occur in the absence of symptoms, and may not be reliably detected by ordinary clinical exam. CNS depressant effects may persist in some patients for up to several days after discontinuing Suvorexant.


Mechanism of Action:


MK-4305 is a dual antagonist of orexin receptors OX1R and OX2R. It exerts its pharmacological effect by inhibiting binding of neuropeptides orexin A and B, also known as hypocretin 1 and 2, that are produced by neurons in the lateral hypothalamus. These neurons control the wake-promoting centers of the brain and are active during wakefulness, especially during motor activities, and stop firing during sleep. By inhibiting the reinforcement of arousal systems, suvorexant use causes a decrease in arousal and wakefulness, rather than having a direct sleep-promoting effect.


Hypnotic d rugs:


MK-4305 is a new hypnotic d rug developed by the US pharmaceutical giant Merck. Unlike other hypnotics, instead of being administrated on demand like general hypnotics (that is, they are taken only when needed), Merck's Suvorexant is a therapeutic d rug, should be subject to long-term administration.


Orexins usually transduces a variety of sobering messages for the human body, being the culprit leading to insomnia. Suvorexant can block Orexins to send messages, it is helpful to better sleep.


Professor Andrew Krystal from the Center for Medical Research at Duke University said Merck's d rug would become a new d rug favored by patients.Darryle Schoepp, the head of neurology and ophthalmology at Merck, says MK-4305 is especially suitable for patients who have been unable to sleep all night and have received little benefit from existing medications.


Suvorexant, sold under the trade name Belsomra, is a medication for the treatment of insomnia.It is effective for insomnia, at least for four weeks and as compared to a placebo.


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ABOUT US

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We're specialized in pharma raw materials ( hormone steroid powders, Steroids injectable liquids,peptides,Sarms), our company integrates R&D, producing, operating and marketing into an organic whole. We have authority of export and import, and have experience of export for 15 years. 


Major Market: United States, United Kingdom, Australia, Canada, Sweden, Russia, Poland, Brazil, Israel, Netherlands, Germany,Spain, Switzerland, Poland and so on.


MOQ:10g

Package:Disguised & Discreet pkg

Payment:T/T,Western Union,Moneygram,bitcoin

Delivery: sent out the goods within 24hours after receiving payment.

Custom Pass rate:99%

Resend policy is available if the parcle is seized or any quality problems been found.


After-sale Service :

Discounts are available for our second-time customers. We can provide recipes and professional suggestions to promote yourselves. Tracking number and packing photos can be given quickly after your goods sent. We are always here waiting for you!


Our main products are wait for you: 

Anabolic Steroid Powders 

Semi-finished Steroid liquid

Peptides

Male enhancement powder 

Pain Killer Powders 

Nootropic Agent

SARMs

Fat Loss 

Solvents for Steroids: BA, BB, GSO, Guaiacol, EO, PEG etc.

Tools & Devices: Filter,Crimper,Vials, caps, ect. 


Sleep AidCAS NO.
Melatonine 73-31-4 
Phenibut 1078-21-3 
Suvorexant(MK-4305) 1030377-33-3 
Agomelatine 138112-76-2 
Trazodone HCL 25332-39-2 
Sertraline HCL 79559-97-0 
gamma-Oryzanol11042-64-1
Trifluoperazine dihydrochloride440-17-5
Sulpiride15676-16-1
Levosulpiride23672-07-3
 Chloral hydrate302-17-0
Tianeptine Sodium 30123-17-2 
NSI-189 1270138-40-3 
NSI-189 Phosphate 1270138-41-4
Tianeptine 66981-73-5 
Tianeptine Sulfate 1224690-84-9 
5-HTP 56-69-9
Escitalopram Oxalate 219861-08-2 


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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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