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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Barbituric Acid 67-52-7 Pharmaceutical Intermediate Powder manufacturer

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Barbituric Acid 67-52-7 Pharmaceutical Intermediate Powder 

Price: 90.0 USD 
Payment Terms: T/T,WU,Money Gram 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Means of Transport: Ocean,Land,Air
Packing: disguise package or as requ...
Brand Name: gongchuang
Purity: 99%
source: Barbituric Acid source
supplier: Barbituric Acid supplier
Usage: Barbituric Acid Usage
purity: 99% min
Standard: USP/BP/USP
Production Capacity: 500kg//month
Delivery Date: 4-15days
CAS No.: 67-52-7
Alias: Barbituric Acid
usage: Barbituric Acid usage
price: Barbituric Acid price
effects: Barbituric Acid
Appearance: powder

Pharmaceutical Intermediate Barbituric Acid CAS: 67-52-7;
Barbituric Acid 67-52-7 Pharmaceutical Intermediate Powder;
Barbituric Acid Powder

Barbituric acid

Product Synonyms: SPECS AG-670/31547005;TIMTEC-BB SBB004242;PYRIMIDINE TRIONE;N,N'-MALONYLUREA;2,4,6-Pyrimidinetriol;2,4,6-pyrimidinetrione;2,4,6-Pyrimidinetrione(1H,3H,5H);2,4,6-Trioxohexahydropyrimidine

CAS:67-52-7

Assay: 99%

MF: C4H4N2O3

MW:128.09

Storage:Store tightly closed in a cool, dry place

Pharmaceutical 99% White Powder Barbituric Acid 67-52-7

Barbituric Acid Info:

Product Name: Barbituric Acid
Synonyms:Pyrimidine Trione;n,n'-Malonylurea;2,4,6-Pyrimidinetriol;2,4,6-Pyrimidinetrione;
2,4,6-Pyrimidinetrione(1h,3h,5h);2,4,6-Trioxohexahydropyrimidine
CAS: 67-52-7
MF:C4H4N2O3
MW:128.09
EINECS:200-658-0
Melting point:248-252 °C (dec.)(lit.)
Boiling point:260ºC
Water Solubility:142 g/L (20 ºC)
Chemical Properties:White crystalline powder. Odorless. Soluble in water and ether, insoluble in water and alcohol.
Uses :It is used for intermediate of organic synthesis raw materials, pharmaceuticals, plastics and dyes. It Is the intermediate of , vitamin B12 and other drug,it is also used as a polymerization catalyst and the preparation of benzimidazolone-based organic pigments. Also it is used as colorimetric determination of uronic and pentosan reagents.
Definition:ChEBI: A barbiturate, the structure of which is that of perhydropyrimidine substituted at C-2, -4 and -6 by oxo groups. Barbituric acid is the parent compound of barbiturate drug, although it is not itself pharmacologically active.
Packing:25kg/drum





Production Method:

It is derived By the reaction of diethyl malonate and urea. First put Urea in a reaction tank containing methanol ,heat , reflux , dissolve, then add the dried diethyl malonate and sodium methoxide, the reaction is refluxed at 66-68 ºC for 4-5h, after distillation to recover methanol, cooling to 40-50 ºC, add dilute hydrochloric acid to adjust to pH 1-2.Cool to room temperature, throw to obtain crude, wash with distilled water once, dry to get crude , and then purify with water and activated carbon, dry to obtain products. Industrial barbituric acid is white or pink crystalline powder, strongly acidic, more than 98% content, melting point ≥245 ºC. Material consumption fixed: diethyl malonate 1098kg/t, urea 476kg/t, hydrochloric acid (reagent grade ) 681kg/t, sodium methanol (28%) 369kg/t, methanol 1025kg/t.


 

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 Factory supply high quality  Barbituric Acid Powder  72846-00-5

1.  Quick Detail:
 
Product Name: Barbituric Acid
Other Name: 2, 4, 6-Tri-hydroxy-pyridine
CAS No.: 67-52-7
EINECS: 200-658-0
Appearance: Off-white crystalline powder
Melting point: 253° C
Loss on drying: < 0.03
Shlohaited ash: ≤ 0.01%
Assay: 99.4%

2.  Description:
 
Barbituric acid or malonylurea or 6-hydroxyuracil is an organic compound based on a pyrimidine heterocyclicskeleton. It is an odorless powder soluble in water. Barbituric acid is the parent compound of barbiturate drug, although barbituric acid itself is not pharmacologically active.
 
3.  Applications:

Using the Knoevenagel condensation reaction, barbituric acid can form a large variety of barbiturate drug that behave as central nervous system depressants. As of 2007, more than 2550 barbiturates and related compounds have been synthesised, with 50 to 55 in clinical use around the world at present. The first to be used in medicine was(Veronal) starting in 1903, and the second,  was first marketed in 1912.
Barbituric acid is one of four ingredients used to make riboflavin (vitamin B2).

4.  Specification:
     


Analysis Item

Result

Appearance

Similar white crystalline powder

Assay

99.3%

Melting point

253.5ºC

Loss on drying

0.1%

Sulphated ash

0.065 %

Conclusion

Complies with Enterprise Standard


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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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