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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Pharmaceutical Material Glimepiride CAS 93479-97-1 for Diabetes Treatment manufacturer

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Pharmaceutical Material Glimepiride CAS 93479-97-1 for Diabetes Treatment 

Price: 90.0 USD 
Payment Terms: T/T,WU,Money Gram 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Means of Transport: Ocean,Land,Air
Packing: disguise package or as requ...
Brand Name: gongchuang
Purity: 99%
source: Glimepiride source
supplier: Glimepiride supplier
Usage: Glimepiride Usage
purity: 99% min
Standard: USP/BP/USP
Production Capacity: 500kg//month
Delivery Date: 4-15days
CAS No.: 93479-97-1
Alias: Glimepiride
usage: Glimepiride usage
price: Glimepiride price
effects: Glimepiride
Appearance: powder

Pharmaceutical Material Glimepiride CAS 93479-97-1 for Diabetes Treatment;
Antihypertensive Drug Glimepiride Effective Powder 93479-97-1;
Glimepirid

Antihypertensive Drug Glimepiride Effective Powder 93479-97-1


Basic Information:

Glimepiride 
Synonyms: 1h-pyrrole-1-carboxamide,2,5-dihydro-3-ethyl-4-methyl-n-(2-(4-(((((4-methylcyc;glimepirid;hoe490;trans-lohexyl)amino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-oxo;GLIMEPIRIDE;1-[[p-[2-(3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea;amary;AMARYL 
CAS: 93479-97-1 
MF: C24H34N4O5S 
MW: 490.62 
Product Categories: Active Pharmaceutical Ingredients;APIs;Intermediates & Fine Chemicals;Pharmaceuticals;Monovalent Ion Channels;Potassium Channel Modulators;Voltage-gated Ion Channels;API's;Chiral Reagents;Heterocycles;Sulfur & Selenium Compounds;API;NEURONTIN;Diabetes Research 
MP: 212.2-214.5 °C
Storage temp.  Room temp 
Solubility  DMSO: >10 mg/mL
Form: solid
Color: white
Chemical Properties White Cyrstalline Solid 
Usage1: anticonvulsant 
Usage2: For concomitant use with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus. 
Usage3: A sulfonylurea hypoglycemic agent. Used as an antidiabetic.

Descriptions:

Glimepiride is used to treat high blood sugar levels caused by type 2 diabetes. It may be used alone, or in combination with insulin or another oral medicine such as metformin. In type 2 diabetes, insulin produced by the pancreas is not able to get sugar into the cells of the body where it can work properly. Using this medicine will help lower blood sugar when it is too high and help restore the way you use food to make energy. . Some people can control type 2 diabetes with diet alone or diet and exercise. Following a specially planned diet and exercising will always be important when you have diabetes, even when you are taking medicines. To work properly, the amount of glimepiride you take must be balanced against the amount and type of food you eat and the amount of exercise you do. If you change your diet, your exercise, or both, you will want to test your blood sugar to find out if it is too low. 

Mechanism of action:

Main article: Sulfonylurea
Like all sulfonylureas, glimepiride acts as an insulin secretagogue.It lowers blood sugar by stimulating the release of insulin by pancreatic beta cells and by inducing increased activity of intracellular insulin receptors.

Not all secondary sufonylureas have the same risks of hypoglycemia. Glibenclamide (glyburide) is associated with an incidence of hypoglycemia of up to 20-30%, compared to as low as 2% to 4% with glimepiride. Glibenclamide also interferes with the normal homeostatic suppression of insulin secretion in reaction to hypoglycemia, whereas glimepiride does not. Also, glibenclamide diminishes glucagon secretion in reaction to hypoglycemia, whereas glimepiride does not.


Product Name: Glimepiride 
Synonyms: 1h-pyrrole-1-carboxamide,2,5-dihydro-3-ethyl-4-methyl-n-(2-(4-(((((4-methylcyc;glimepirid;hoe490;trans-lohexyl)amino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-oxo;GLIMEPIRIDE;1-[[p-[2-(3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea;amary;AMARYL 
CAS: 93479-97-1 
MF: C24H34N4O5S 
MW: 490.62 
Product Categories: Active Pharmaceutical Ingredients;APIs;Intermediates & Fine Chemicals;Pharmaceuticals;Monovalent Ion Channels;Potassium Channel Modulators;Voltage-gated Ion Channels;API's;Chiral Reagents;Heterocycles;Sulfur & Selenium Compounds;API;NEURONTIN;Diabetes Research 
MP: 212.2-214.5 °C
Storage temp.  Room temp 
Solubility  DMSO: >10 mg/mL
Form: solid
Color: white
Chemical Properties White Cyrstalline Solid 
Usage1: anticonvulsant 
Usage2: For concomitant use with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus. 
Usage3: A sulfonylurea hypoglycemic agent. Used as an antidiabetic.

CERTIFICATE OF ANALYSIS


Product name

Glimepiride

CAS No.

93479-97-1

Outer Packing

25KG/drum

Production date

2017.7.12

Shelf life

2020.07.11

Standard adopted

Enterprise standard

Items of analysis

Specification

Results

Appearance

White or off white powder

off white powder
Solubility
Two soluble in dimethylformamide, soluble in dichloromethane two chloride, slightly soluble in methanol, practically insoluble in water

Conforms

Identification

IR map should be consistent with the control map

Conforms

Heavy metal

≤10 ppm

Conforms
A
Cis-isomer(A)

≤0.8%

0.20%
B
Sulfonamide(B)

≤0.4%

0.11%
C
Urethane(C)

≤0.1%

ND
D
3-isomer(D)

≤0.2%

ND

Any other impurity

≤0.1%

0.08%

Total impurities

≤0.5%

0.12%

Residue on ignition

≤0.2%

0.08%

Loss on drying

≤0.5%

0.16%

Assay

98.0% ~102.0 %

99.36%

Conclusion

Qualified

 


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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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