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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Telmisartan CAS 144701-48-4 for Hypertension Treatment manufacturer

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Telmisartan CAS 144701-48-4 for Hypertension Treatment 

Price: 90.0 USD 
Payment Terms: T/T,WU,Money Gram 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Means of Transport: Ocean,Land,Air
Packing: disguise package or as requ...
Brand Name: gongchuang
Purity: 99%
source: Telmisartan source
supplier: Telmisartan supplier
Usage: Telmisartan Usage
purity: 99% min
Standard: USP/BP/USP
Production Capacity: 500kg//month
Delivery Date: 4-15days
CAS No.: 144701-48-4
Alias: Telmisartan
usage: Telmisartan usage
price: Telmisartan price
effects: Telmisartan
Appearance: powder

Raw Material Telmisartan for Antihypertensive Treatment of Hypertension;
Telmisartan CAS 144701-48-4 for Hypertension Treatment;
Telmisartan

1.Basic Info:
 

Product NameTelmisartan
CAS144701-48-4
MFC33H30N4O2
MW514.63
Purity99%
AppearanceWhite or off-white crystalline powder
Usagecardiotonic. an angiotensin II receptor antagonist. anti-cancer agent
CategoriePharmaceutical material and intermeidates;Active Pharmaceutical Ingredients;INTERMEDIATESOF;Antihypertensive;Imidazoles;(intermediates of telmisartan);Telmisartan;Hypertension;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Other Products;Hypertension.;CARADRIN
SynonymsTU-199;TELMISARTAN;PRITOR;MICARDIS;BIBR 277;
4'[(1,4'-DIMETHYL-2'-PROPYL[2,6'-BI-1H-BENZIMIDAZOL]-1'-YL)METHYL][1,1'-BIPHENYL]-2-CARBOXYLIC ACID;
4'-[(1,4'-DIMETHYL-2'-PROPYL[2,6'-BI-H-BENZIMIDAZOL]-1'-YL)METHYL][1,1'-BIPHENYL]-2-CARBOXYLIC ACID;
3-methoxy-8-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methyl sulfinyl]-2,7,9-triazabicyclo[4.3.0]nona-2,4,8,10-tetraene


COA:

ItemsSpecificationResults
AppearanceWhite or slightly yellowish crystalline powderWhite crystalline powder
SolubilityShould meet the requirementConforms
IR IdentificationShould correspond to the RS Infrared AbsorptionCorrespond to the reference substance
Appearance of solutionShould meet the requirementConforms
Loss on drying≤0.5%0.20%
Sulphated ash≤0.1%Conforms
Melting point261 ºC -263 ºC261.1 ºC -262.2 ºC
Particle size90% Less than 200umConforms
Assay99.0%~101.0%99.9%
ConclusionIt conforms to European Pharmacopoeia 7.0






2.Description

Telmisartan (Micardis) is an oral prescription medication most commonly used to treat hypertension, including mild hypertension where blood pressure is only moderately elevated or borderline. If choosing to self-medicate for mild hypertension or borderline high blood pressure, telmisartan is an excellent or even best choice.

As elevated blood pressure is often an undesired side effect of anabolic steroid cycles and can even limit use of androgens, this use of telmisartan is already enough to make the drug of value to many.
However, telmisartan also has an entirely different category of use, due to having quite a number of other interesting properties which can be valuable in some instances.

Benefits can include improvement to fat loss, endurance, insulin sensitivity, reduction of risk of atherosclerosis, stroke, and of heart attack, and possible benefit to brain health. In some cases mood or energy can be improved as well.




3.Application :

1. Telmisartan is an angiotensin II receptor antagonist. Telmisartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

2. Telmisartan is used to treat high blood pressure (hypertension). It is sometimes given together with other blood pressure medications.

3. Telmisartan is also used to reduce the risk of stroke, heart attack, or death from heart problems in people who are at least 55 years old with risk factors for serious heart disorders.




4.When to use telmisartan

If blood pressure needs to be moderated, I'd certainly consider using telmisartan. If there is no such need, factors that could suggest its use include interest in reducing visceral fat, of improving impaired insulin sensitivity, of reducing risk of atherosclerosis, or depending on personal interest, of possibly improving brain health and function.

Reasons not to use telmisartan could include unwillingness to accept the risk of possible side effects, or unwillingness to shift the balance of fat loss towards visceral fat loss versus subcutaneous fat loss. In general, if dieting and training achieve only the same bodyfat percentage despite the positive effects of telmisartan, appearance could be smoother due to the same amount of bodyfat being present but with less of it stored as unhealthful visceral fat.
On the other hand, if taking advantage of improved loss of visceral fat with telmisartan to achieve a lower bodyfat percentage, then there's no smoothness penalty. However, when aiming for contest condition there's a certain amount of fat that the body must retain: theoretically, reducing visceral fat in this case might force retention of a greater amount of subcutaneous fat. So I wouldn't advise telmisartan use in the last few weeks before a bodybuilding contest.




5.How to use telmisartan

To reduce risk of atherosclerosis, cardiovascular disease, or stroke where risk is only moderate in the first place, I suggest a dose from 20 to 40 mg taken orally once per day. Dosing would be the same where the interest is slowing loss of brain function with age, or potentially improving brain function.

For possible improvement in fat loss, particularly of visceral fat, or improvement of endurance I suggest dosing of 80-160 mg/day. Starting dose, however, generally should be only 40 mg/day until tolerance is assessed.

While it's not required and telmisartan users in general do not do so, when using this drug I suggest supplementing with oleuropein 200-400 mg/day and Vitamin D 5000 IU/day. These are to reduce or perhaps eliminate two activities of telmisartan that I would not consider desirable for physique or performance enhancement, though they add to its medical use.

Telmisartan should not be used in combination with a diuretic, and I would avoid allowing severe dehydration while using this drug.

Blood pressure should be monitored while using telmisartan. Typically, any decrease of blood pressure is simply to healthful levels or more-nearly healthful levels, and those who do not have high blood pressure see no decrease with telmisartan. Still, there can be exceptions, so this should be watched.

Lastly, I would cycle telmisartan use rather than use it continuously. There's no proof of what cycling method might be optimal, but for example I'd suggest being "off" about as many weeks per year as "on" as a minimum. This is not because of proven problem, but simply because I expect the benefits can be fully or nearly fully realized with this amount of use, and where any of the changes to gene expression or receptor blocking might be adverse in the individual case rather than beneficial, this will then be no more than half the time.


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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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