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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Pharmaceutical Antidepressant Raw Material Sertraline Hydrochloride CAS 79559-97-0 manufacturer

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Pharmaceutical Antidepressant Raw Material Sertraline Hydrochloride CAS 79559-97-0 

Price: 1.0 USD 
Payment Terms: T/T,WU,Money Gram 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: pharma raw powder
Production Capacity: 5000kg per month
Delivery Date: within 24 hours after payme...
CAS No.: 79559-97-0
Sertraline HCl color: white
Sertraline Hydrochloride Alias: 79559-97-0
Sertraline Hydrochloride Standard: USP
Sertraline Hydrochloride methods: T/T, Westeron Union, Money ...
Sertraline Hydrochloride Delivery time: 5-7 day
Means of Transport: Ocean,Air;express
Packing: disguised package
Brand Name: Sertraline HCl
Purity: 99%
Sertraline HCl appearence: powder
Sertraline Hydrochloride Formula: C13H19Cl2NO
Sertraline Hydrochloride package: foil bag or as you mind
Sertraline Hydrochloride lead time: within 24hour after payment...
Sertraline Hydrochloride Usage: Antidepressant

Sertraline HCL is a selective serotonin reuptake inhibitor.
Sertraline HCL is used as an antidepressant drug.
Sertraline HCL in mass stock


Sertraline HCL Quick Details


Name: Sertraline HCL

Synonyms:(1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-N-Methyl-1-Naphthalenamine Hydrochloride;(1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-N-Methyl-1-Napthalenamine Hydrochloride;(1S,4S)-1-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-4-(Methylamino)Naphthalene Hydrochloride;N-(4(3,4-Dichlorophenyl)-3,4-Dihydro-1(2H)Naphthalidene) Methanamine;Sertraline Mandelate
CAS:79559-97-0
MF:C13H19Cl2NO

MW:342.69
EINECS:200-659-6
Chemical Properties:White Crystalline Powder
Melting point:246-249°C
Solubility:DMSO: ~26 mg/mL
Uses :A selective serotonin reuptake inhibitor. Used as an antidepressant.
Definition: A hydrochloride resulting from the reaction of equimolar amounts of sertraline and hydrogen chloride. A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as an antidepressant for the treatment of depression, obsessive-compulsive diso der, panic disorder and post-traumatic stress disorder.
Biological Activity:Potent, orally active selective serotonin re-uptake inhibitor (SSRI) used clinically to treat depression.

What is Sertraline HCL?

Sertraline HCL is an antidepressant in a group of drug called selective serotonin reuptake inhibitors (SSRIs).
The way the drug works is not yet fully understood. Is thought to positively affect the communication between the nerve cells of the central nervous system and / or restore the chemical balance in the brain.
Sertraline for the treatment of depression, obsessive-compulsive disorder, panic disorder, anxiety, post-traumatic stress disorder (PTSD) and premenstrual anxiety (PMDD).


Sertraline HCL Application


Sertraline is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Sertraline is primarily prescribed for major depressive disorder in adult outpatients as well as obsessive-compulsive disorder, panic disorder, and social anxiety disorder, in both adults and children.

Differences with other newer antidepressants are subtle and mostly confined to side effects. It has a similar tolerability profile to other SSRIs, with the types of adverse events usually including diarrhea, nausea, and sexual dysfunction. The incidence of diarrhea was higher with sertraline-especially when prescribed at higher doses-in comparison to other SSRIs.

Sertraline is used for a number of conditions including: major depression, obsessive-compulsive disorder (OCD), body dysmorphic disorder (BDD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), panic disorder and social anxiety disorder.It has also been used for premature ejaculation and vascular headaches but evidence of the effectiveness in treating those conditions is not robust.


Sertraline HCL Specification


ItemRequirementsTest Results
DescriptionA white or almost white crystalline powderwhite crystalline powder
Identification

IR spectrumConcordant with the working referenceComplies
Discrimination chlorideForward reactionComplies
HPLCConcordant with the working referenceComplies
Related Substances

Total impurities≤1.0%0.6%
Individual impurities≤0.50%0.28%
Sulphated ash≤0.1 %0.04%
Optical rotation+36.0   ~ 42.0+39.2
SolubilityInsoluble in dimethyl sulfoxide and sparingly soluble in methanolComplies
Melting point242 ~ 248ºC243ºC ~ 245ºC
Loss on drying≤ 0.5 %0.13%
Heavy metals≤20ppm<10ppm
Assay [C18 ODS colum]98.5 % ~101.5 %(on dried basis)99.7%
Assay [with chiral colum]≥97.0 %97.8 %
ConclusionMeets the Requirements



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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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