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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Pharmaceuticals Raw Powder Octenidine Dihydrochloride for Antibacterial manufacturer

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Pharmaceuticals Raw Powder Octenidine Dihydrochloride for Antibacterial 

Qty (Other,ml) Unit Price (160.0~290.0 USD)
100 - 199 160
200 + 290
Payment Terms: T/T,WU,Money Gram;bitcoin 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: HKYC
Production Capacity: 100000L/WEEK
Delivery Date: with 6 working hours
service: resend guarantee
Supply Ability: Mass Stock
Model Number: 70775-75-6
Usage: Pharmaceutical Raw
Shipping: 3-7 Days / Door-to-Door
Means of Transport: Air
Packing: brand new
package: Special disguised packaging...
Payment Terms: Western Union, MoneyGram, B...
Certification: ISO
Active-Life: 7-9 days
Lead Time: Within 12 Hours After Payme...

Pharmaceuticals Raw Powder Octenidine Dihydrochloride for Antibacterial
Pharmaceuticals Raw Powder Octenidine Dihydrochloride for Antibacterial

Topical Pharmaceuticals Raw Powder Octenidine Dihydrochloride for Antibacterial


Quick Detail

Product Name
Octenidine Dihydrochloride
 
Synonym
N,N'-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylammonium) dichloride;ocenidine dihydrochloride;1-OctanaMine,N,N'-(1,10-decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-, hydrochloride
 
CAS
70775-75-6
 
MF
C36H64Cl2N4
 
MW
623.82616
 
EINECS
274-861-8
 
Melting Point
215-217ºC
 
Solubility
Soluble in dimethyl sulfoxide and methanol.
 
Appearance
White powder
 
Grade
Pharma Grade
 
Usage
It is a substitute for chlorhexidine, with respect to its slow action and concerns about the carcinogenic impurity 4-chloroaniline. Octenidine antiseptics often contain phenoxyethanol.
 



Introduction

Octenidine dihydrochloride is a topical antimicrobial used in personal care and medical industry. It is similar in its action to the quaternary ammonium compounds (quats), but is of somewhat broader spectrum of activity.

Octenidine is currently increasingly used in continental Europe as a substitute for quats or chlorhexidine (with respect to its slow action and concerns about the carcinogenic impurity 4-chloroaniline) in water- or alcohol-based skin, mucosa and wound antiseptics. In aqueous formulations, it is often potentiated with addition of 2-phenoxyethanol.  

As topical antimicrobial agents, Octenidine is typically used for skin, mu­cous membrane and open wound decontamination. Octenidine meets the need for a broad-spectrum antimicrobial suitable for wound care.   

First launched in the UK during 1990, octenidine is available in three formulations in the UK: octenilin® wound gel (0.05% octenidine); octenilin® wound irrigation solution (0.05% octenidine); and octenisan® wash lotion (0.3% octenidine) for decolonisation.   

Octenidine is more active than 4% chlorhexidine against S aureus, Staphylococcus epidermidis, Proteus mirabilis, Streptococcus pyogenes, Klebsiella pneumoniae, Escherichia coli  and Candida albicans, etc.   

At concentrations of <1.5μM, octenidine reduced numbers of these bacteria by 99% within 15 minutes.

However, the wound environment may modify bacteriological potency recorded in culture: 8% serum reduces the effectiveness of chlorhexidine between 2.5 and 35-fold. In vitro, the addition of pus or 25% blood reduces chlorhexidine's effectiveness by around 1-log step. In contrast, blood (up to 10%), albumin and mucin do not undermine octenidine's efficacy. This observation suggests that products containing octenidine retain antibacterial efficacy when applied to wounds.

Free Sample White Powder Octenidine Dihydrochloride 10g/50g/100g/1kg CAS No.: 70775-75-6 

Product Description  
 

Product Name
Octenidine Dihydrochloride
 
Synonym
N,N'-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylammonium) dichloride;ocenidine dihydrochloride;1-OctanaMine,N,N'-(1,10-decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-, hydrochloride
 
CAS
70775-75-6
 
MF
C36H64Cl2N4
 
MW
623.82616
 
EINECS
274-861-8
 
Melting Point
215-217ºC
 
Solubility
Soluble in dimethyl sulfoxide and methanol.
 
Appearance
White powder
 
GradePharma Grade
 
Usage
It is a substitute for chlorhexidine, with respect to its slow action and concerns about the carcinogenic impurity 4-chloroaniline. Octenidine antiseptics often contain phenoxyethanol.
 


Attention please: We can provide the sample,but not for the freight.The freight is according to the actual situation of each country.

Introduction

Octenidine dihydrochloride is a topical antimicrobial used in personal care and medical industry. It is similar in its action to the quaternary ammonium compounds (quats), but is of somewhat broader spectrum of activity.

Octenidine is currently increasingly used in continental Europe as a substitute for quats or chlorhexidine (with respect to its slow action and concerns about the carcinogenic impurity 4-chloroaniline) in water- or alcohol-based skin, mucosa and wound antiseptics. In aqueous formulations, it is often potentiated with addition of 2-phenoxyethanol.  

As topical antimicrobial agents, Octenidine is typically used for skin, mu­cous membrane and open wound decontamination. Octenidine meets the need for a broad-spectrum antimicrobial suitable for wound care.   

First launched in the UK during 1990, octenidine is available in three formulations in the UK: octenilin® wound gel (0.05% octenidine); octenilin® wound irrigation solution (0.05% octenidine); and octenisan® wash lotion (0.3% octenidine) for decolonisation.   

Octenidine is more active than 4% chlorhexidine against S aureus, Staphylococcus epidermidis, Proteus mirabilis, Streptococcus pyogenes, Klebsiella pneumoniae, Escherichia coli  and Candida albicans, etc.   

At concentrations of <1.5μM, octenidine reduced numbers of these bacteria by 99% within 15 minutes.

However, the wound environment may modify bacteriological potency recorded in culture: 8% serum reduces the effectiveness of chlorhexidine between 2.5 and 35-fold. In vitro, the addition of pus or 25% blood reduces chlorhexidine's effectiveness by around 1-log step. In contrast, blood (up to 10%), albumin and mucin do not undermine octenidine's efficacy. This observation suggests that products containing octenidine retain antibacterial efficacy when applied to wounds.


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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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