Post Offer Free
Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Sarm Powder Sr9011 / Sr9009 / Yk-11/ Rad140 / Mk-677 manufacturer

2nd

Gold Index: 167643

You are here: home  > Sarm Steroid Powders  > Sarm Powder Sr9011 / Sr9009 / Yk-11/ Rad140 / Mk-677

Sarm Powder Sr9011 / Sr9009 / Yk-11/ Rad140 / Mk-677 

Qty (Other,ml) Unit Price (160.0~290.0 USD)
100 - 199 160
200 + 290
Payment Terms: WU,Money Gram 
Place of Origin: Hubei, China (Mainland) 
inquire skype
Add to My Favorites
HiSupplier Escrow
Share |

Product Detail

Model No.: HKYC
Production Capacity: 100000L/WEEK
Delivery Date: with 6 working hours
service: resend guarantee
Supply Ability: Mass Stock
Model Number: 159752-10-0
Usage: Pharmaceutical Raw
Shipping: 3-7 Days / Door-to-Door
Means of Transport: Air
Packing: brand new
package: Special disguised packaging...
Payment Terms: Western Union, MoneyGram, B...
Certification: ISO
Active-Life: 7-9 days
Lead Time: Within 12 Hours After Payme...

Sarm Powder Sr9011 / Sr9009 / Yk-11/ Rad140 / Mk-677
Sarm Powder Sr9011 / Sr9009 / Yk-11/ Rad140 / Mk-677
Sarm Powder Sr9011 / Sr9009 / Yk-11/ Rad14

Quick detail

Product NameSR9011
Chemical NameSR9011
CAS Number1379686-29-9
EINECS Number212-729-3
Molecular FormulaC14H12F6N2O
Molecular Weight338.2482992
Molecular Structure
Assay99.5%
AppearanceWhite powder

what is SR9011?
 
SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates. Recommended for use in peroxide cured coatings, sealants, and PCV-based plastisols. Performance properties include: good adhesion, good chemical resistance, good hardness, good heat resistance and high abrasion resistance.
 
Biological Activity:
 
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism.

Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.
 
 How to Use:
 
In vitro: SR9011 was used at 5-10 µM concentration in vitro and in cellular assays.
In vivo: IP administration of SR9011 was used at 100 mg/kg once or twice per day for 12-30 days in different mouse models.
 


Packing&Storage

 

 

Packaging Detail

0.5kgs/Al-Bottle
1.0kgs/Al- Bottle
2.0kgs/Al- Bottle
5.0 kgs/Al-Bottle
25.0 kgs/drum
or upon customers' request.

Storage

Store in a well-closed container away from moisture

Shelf Life

2 years if sealed and store away from direct sun light.

Delivery Detail

Within 3 days after get the payment 


Ms. Gina
skype Ms. Gina
Manager
Tel: 86-27-88211875
Mobile: 188 7222 0799
Contact to this supplier

Didn't find what you're looking for? Post Buying Lead or contact HiSupplier Customer Service Center  for help!

Related Search

Find more related products in following catalogs on Hisupplier.com

Other products from this supplier

Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

Follow Us: Follow us on facebook Follow us on linkedin Follow us on Twitter

Gina:   skype
Service:   skype

You May Like: