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Wuhan Yuancheng Gongchuang Technology Co,ltd
Wuhan Yuancheng Gongchuang Technology Co,ltd

China Donepezil Hydrochloride Aricept Nootropic Agent Powder manufacturer

2nd

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Donepezil Hydrochloride Aricept Nootropic Agent Powder 

Qty (Other,ml) Unit Price (160.0~290.0 USD)
100 - 199 160
200 + 290
Payment Terms: WU,Money Gram 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Model No.: 120011-70-3
Production Capacity: 100000L/WEEK
Delivery Date: with 6 working hours
service: resend guarantee
Supply Ability: Mass Stock
Model Number: 120011-70-3
Usage: Pharmaceutical Raw
Shipping: 3-7 Days / Door-to-Door
Means of Transport: Air,Air
Packing: brand new
package: Special disguised packaging...
Payment Terms: Western Union, MoneyGram, B...
Certification: ISO
Active-Life: 7-9 days
Lead Time: Within 12 Hours After Payme...

Donepezil Hydrochloride Aricept Nootropic Agent Powder
Donepezil Hydrochloride Aricept Nootropic Agent Powder
Donepezil Hydrochloride Aricept N

Donepezil Hydrochloride (Aricept) Nootropic Agent CAS 120011-70-3

Chemical Name:donepezil hydrochloride
Application:antimuscarinic 
Donepezil hydrochloride
Molecular Formula:C24H30ClNO3
Formula Weight:415.95
CAS:120011-70-3
Purity:99%
Appearance:white powder

Introduction  

ARICEPT (donepezil hydrochloride) is a reversible inhibitor of the enzyme acetylcholinesterase, known chemically as (±)-2, 3-dihydro-5, 6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1Hinden- 1-one hydrochloride. Donepezil hydrochloride is commonly referred to in the pharmacological literature as E2020. It has an empirical formula of C24H29NO3HCl and a molecular weight of 415.96. Donepezil hydrochloride is a white crystalline powder and is freely soluble in chloroform, soluble in water and in glacial acetic acid, slightly soluble in ethanol and in acetonitrile, and practically insoluble in ethyl acetate and in n-hexane.
Benefits of Sitagliptin Phosphate Monohydrat

Donepezil hydrochloride is a therapeutic treatment of Alzheimer's drug , compared with similar drug  have a low incidence of adverse reactions and efficacy obvious feature is the only way to reach the U.S. Food and Drug Administration standard treatment guidelines for Alzheimer's disease drug, is the only one species while the FDA approved the listing of new drug  and UK MCA for the treatment of mild to moderate Alzheimer's. 
 
Function
 
Donepezil hydrochloride is a long-acting Alzheimer's disease (AD) in the symptomatic treatment drug . AD is a kind of memory loss as the main performance, accompanied by other cognitive impairment of acquired intelligence decline. Nearly 30 years of research show: AD progressive degeneration of cholinergic neurons is memory loss, disorientation, personality changes and behavioral reasons, such cholinergic theory has been confirmed by histological study.

Donepezil hydrochloride is a second-generation cholinesterase (ChE) inhibitor, its therapeutic effect is reversibly inhibiting acid hydrolysis of acetylcholine acetylcholinesterase (AchE) caused by increased content of acetylcholine receptor sites. Donepezil may have other mechanisms, including the disposal of the direct effect of the peptide, neurotransmitter receptors, or Ca2 + channels.
 
Donepezil hydrochloride selection of AchE affinity than to butyrylcholinesterase (BchE) 1250 times stronger, it can inhibit the brain tissue ChE, but on the heart (myocardium) or small intestine (smooth) had no effect, probably on the chest organization (rhabdomyosarcoma) role; on the central nervous toxicity than tacrine.

Sitagliptin Phosphate Monohydrat COA 
 

Product nameDonepezil hydrochloride
Synonyms2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one hydrochloride
CAS No.120011-70-3
Molecular formulaC24H29NO3.HCl
Molecular weight415.95
Specifications
ITEMSSPECIFICATIONSRESULTS
APPEARANCEWHITE OR ALMOST WHITE CRYSTALLINE POWDERCONFORMS
SOLUBILITYTO MATCH WORKING STANDARDCONFORMS
IDENTIFICATION1) BY UV ABSORPTION,TO MATCH WORKING STANDARD
2) BY IR ABSORPTION,TO MATCH WORKING STANDARD
CONFORMS
 
 
CONFORMS
PH4.0-7.05.47
MELTING POINT216-220°C218-220°C
RELATED SUBSTANCE
TOTAL≤1.80%0.07%
SINGLE IMPURITY (UNKNOWN)≤0.50%<0.1%
LOSS ON DRYING≤1.0%0.03%
RESIDUE ON IGNITION≤0.10%0.08%
HEAVY METAL≤10 PPM<10 PPM
ASSAY≥99.0%99.75%
CONCLUSIONCONFORMS TO THE ENTERPRISE STANDARD


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Company Info

Wuhan Yuancheng Gongchuang Technology Co,ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Wuhan
Province/State: Hubei
Country/Region: China (Mainland)

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